Inferior Petrosal Venous Sinus Sampling

Part of the Techniques in Interventional Radiology book series (TECHRAD)


Cushing’s syndrome (CS) is most commonly due to exogenous glucocorticoid administration. The most common endogenous cause of CS (70–80 %) is an adrenocorticotropic hormone (ACTH)-secreting pituitary adenoma (Cushing’s disease) for which the treatment of choice is surgical excision. Confirming the diagnosis of a pituitary source and excluding ectopic sources of ACTH using biochemical testing and cross-sectional imaging are often challenging.


Cushing’s syndrome Exogenous glucocorticoid administration Adrenocorticotropic hormone-secreting pituitary adenoma Pituitary adenoma Adenoma Cushing’s disease Surgery Ectopic source Biochemical testing Cross-sectional imaging Bilateral interior petrosal sinus sampling Peripheral venous sampling Corticotropin-releasing hormone Sensitivity Specificity Diagnosis 

Suggested Reading

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Copyright information

© Springer-Verlag London 2014

Authors and Affiliations

  1. 1.Department of Interventional RadiologyBarts and the Royal LondonLondonUK
  2. 2.Department of RadiologyBarts and the London NHS TrustLondonUK

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