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Cardiovascular Disease in Endocrine Disorders

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Abstract

Cardiovascular symptoms are often the first signs and symptoms of underlying endocrinopathies. This chapter reviews endocrine disorders with a focus on cardiovascular changes and presentations.

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Abbreviations

ACTH:

Adrenocorticotropic hormone

AF:

Atrial fibrillation

AI:

Adrenal insufficiency

AIT:

Amiodarone-induced thyrotoxicosis

BMD:

Bone mineral density

CAD:

Coronary artery disease

CHF:

Congestive heart failure

CMV:

Cytomegalovirus

CO:

Cardiac output

CV:

Cardiovascular

CVD:

Cardiovascular disease

DBP:

Diastolic blood pressure

DTR:

Deep tendon reflexes

EKG:

Electrocardiogram

GH:

Growth hormone

HIV:

Human immunodeficiency virus

HR:

Heart rate

HTN:

Hypertension

IGF-1:

Insulin-like growth factor - 1

IV:

Intravenous

LV:

Left ventricular

OGTT:

Oral glucose tolerance test

PAC:

Plasma aldosterone concentration

PE:

Physical exam

PRA:

Plasma renin activity

PTH:

Parathyroid hormone

PTU:

Propylthiouracil

PVR:

Peripheral vascular resistance

RAI:

Radioactive iodine

RAIU:

Radioactive iodine uptake

SBP:

Systolic blood pressure

SSKI:

Supersaturated potassium iodide

SV:

Stroke volume

SVR:

Systemic vascular resistance

T3:

Triiodothyronine

T4:

Thyroxine

TB:

Tuberculosis

TFT:

Thyroid function tests

TSH:

Thyroid stimulating hormone

TTE:

Trans-thoracic echocardiography

WNL:

Within normal limits

References

  1. Franklyn JA. The management of hyperthyroidism. N Engl J ­Med. 1994;330(24):1731–8.

    Article  PubMed  CAS  Google Scholar 

  2. Fuster V, Ryden LE, Cannom DS, Crijns HJ, Curtis AB, Ellenbogen KA, et al. 2011 ACCF/AHA/HRS focused updates incorporated into the ACC/AHA/ESC 2006 guidelines for the management of patients with atrial fibrillation: a report of the American College of Cardiology Foundation/American Heart Association Task Force on practice guidelines. Circulation. 2011;123(10):e269–367.

    Article  PubMed  Google Scholar 

  3. Nayak B, Burman K. Thyrotoxicosis and thyroid storm. Endocrinol Metab Clin North Am. 2006;35(4):663–86, vii.

    Article  PubMed  CAS  Google Scholar 

  4. Sawin CT, Geller A, Wolf PA, Belanger AJ, Baker E, Bacharach P, et al. Low serum thyrotropin concentrations as a risk factor for atrial fibrillation in older persons. N Engl J Med. 1994;331(19):1249–52.

    Article  PubMed  CAS  Google Scholar 

  5. Sgarbi JA, Villaca FG, Garbeline B, Villar HE, Romaldini JH. The effects of early antithyroid therapy for endogenous subclinical hyperthyroidism in clinical and heart abnormalities. J Clin Endocrinol Metab. 2003;88(4):1672–7.

    Article  PubMed  CAS  Google Scholar 

  6. Cooper DS. Clinical practice. Subclinical hypothyroidism. N Engl J Med. 2001;345(4):260–5.

    Article  PubMed  CAS  Google Scholar 

  7. Devdhar M, Ousman YH, Burman KD. Hypothyroidism. Endocrinol Metab Clin North Am. 2007;36(3):595–615, v.

    Article  PubMed  CAS  Google Scholar 

  8. Wartofsky L. Myxedema coma. Endocrinol Metab Clin North Am. 2006;35(4):687–98, vii–viii.

    Article  PubMed  CAS  Google Scholar 

  9. Adler SM, Wartofsky L. The nonthyroidal illness syndrome. Endocrinol Metab Clin North Am. 2007;36(3):657–72, vi.

    Article  PubMed  CAS  Google Scholar 

  10. Roti E, Uberti ED. Iodine excess and hyperthyroidism. Thyroid. 2001;11(5):493–500.

    Article  PubMed  CAS  Google Scholar 

  11. Markou K, Georgopoulos N, Kyriazopoulou V, Vagenakis AG. Iodine-Induced hypothyroidism. Thyroid. 2001;11(5):501–10.

    Article  PubMed  CAS  Google Scholar 

  12. Martino E, Bartalena L, Bogazzi F, Braverman LE. The effects of amiodarone on the thyroid. Endocr Rev. 2001;22(2):240–54.

    Article  PubMed  CAS  Google Scholar 

  13. Bogazzi F, Bartalena L, Martino E. Approach to the patient with amiodarone-induced thyrotoxicosis. J Clin Endocrinol Metab. 2010;95(6):2529–35.

    Article  PubMed  CAS  Google Scholar 

  14. Osman F, Franklyn JA, Sheppard MC, Gammage MD. Successful treatment of amiodarone-induced thyrotoxicosis. Circulation. 2002;105(11):1275–7.

    PubMed  CAS  Google Scholar 

  15. Bornstein SR. Predisposing factors for adrenal insufficiency. N Engl J Med. 2009;360(22):2328–39.

    Article  PubMed  CAS  Google Scholar 

  16. Tritos NA, Biller BM, Swearingen B. Management of Cushing disease. Nat Rev Endocrinol. 2011;7(5):279–89 [Review].

    Article  PubMed  CAS  Google Scholar 

  17. Sharma ST, Nieman LK. Cushing’s syndrome: all variants, detection, and treatment. Endocrinol Metab Clin North Am. 2011;40(2):379–91, viii–ix.

    Article  PubMed  CAS  Google Scholar 

  18. Young Jr WF. Adrenal causes of hypertension: pheochromocytoma and primary aldosteronism. Rev Endocr Metab Disord. 2007;8(4):309–20.

    Article  PubMed  CAS  Google Scholar 

  19. Rossi GP. Diagnosis and treatment of primary aldosteronism. Endocrinol Metab Clin North Am. 2011;40(2):313–32, vii–viii.

    Article  PubMed  CAS  Google Scholar 

  20. Melmed S. Medical progress: acromegaly. N Engl J Med. 2006;355(24):2558–73.

    Article  PubMed  CAS  Google Scholar 

  21. Walker MD, Silverberg SJ. Cardiovascular aspects of primary hyperparathyroidism. J Endocrinol Invest. 2008;31(10):925–31.

    PubMed  CAS  Google Scholar 

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Author information

Authors and Affiliations

  1. Harvard Medical School Division of Endocrinology, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA

    Nancy J. Wei MD, MMSc (Instructor in Medicine) & J. Carl Pallais MD, MPH (Assistant Professor of Medicine)

Authors
  1. Nancy J. Wei MD, MMSc
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  2. J. Carl Pallais MD, MPH
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Editor information

Editors and Affiliations

  1. Cardiology Division Yawkey Building 5B, Room 5850, Massachusetts General Hospital, Boston, Massachusetts, USA

    Hanna K. Gaggin

  2. Cardiology Division Yawkey Building, Suite 5984, Massachusetts General Hospital, Boston, Massachusetts, USA

    James L. Januzzi, Jr.

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© 2014 Springer-Verlag London

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Wei, N.J., Pallais, J.C. (2014). Cardiovascular Disease in Endocrine Disorders. In: Gaggin, H., Januzzi, Jr., J. (eds) MGH Cardiology Board Review. Springer, London. https://doi.org/10.1007/978-1-4471-4483-0_32

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  • DOI: https://doi.org/10.1007/978-1-4471-4483-0_32

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  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-4482-3

  • Online ISBN: 978-1-4471-4483-0

  • eBook Packages: MedicineMedicine (R0)

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