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Ventricular Arrhythmias and Defibrillators

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MGH Cardiology Board Review

Abstract

Ventricular tachyarrhythmias have heterogeneous etiologies, clinical consequences, and treatment strategies. Distinguishing ventricular tachyarrhythmias from supraventricular tachycardia (SVT) with aberrancy clinically and on the surface electrocardiogram can be challenging, yet has substantial therapeutic implications. A wide body of randomized clinical trial data has emerged addressing the efficacy of implantable cardioverter defibrillators (ICDs) for the prevention of sudden cardiac death. In this chapter we discuss these issues as well as consensus guideline recommendations for the implantation of ICDs.

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Abbreviations

AAD:

Antiarrhythmic drugs

ACC:

American College of Cardiology

AHA:

American Heart Association

CABG:

Coronary artery bypass grafting

EPS:

Electrophysiology study

HRS:

Heart Rhythm Society

ICD:

Implantable cardioverter defibrillator

LVEF:

Left ventricular ejection fraction

MI:

Myocardial infarction

NSVT:

Nonsustained ventricular tachycardia

NYHA:

New York Heart Association

SVT:

Supraventricular tachycardia

VF:

Ventricular fibrillation

VT:

Ventricular tachycardia

References

  1. Brugada P, Brugada J, Mont L, Smeets J, Andries EW. A new approach to the differential diagnosis of a regular tachycardia with a wide QRS complex. Circulation. 1991;83:1649–59.

    Article  PubMed  CAS  Google Scholar 

  2. Lau EW, Pathamanathan RK, Ng GA, Cooper J, Skehan JD, Griffith MJ. The Bayesian approach improves the electrocardiographic diagnosis of broad complex tachycardia. Pacing Clin Electrophysiol. 2000;23:1519–26.

    Article  PubMed  CAS  Google Scholar 

  3. Hohnloser SH, Kuck KH, Dorian P, Roberts RS, Hampton JR, Hatala R, et al. Prophylactic use of an implantable cardioverter-defibrillator after acute myocardial infarction. N Engl J Med. 2004;351:2481–8.

    Article  PubMed  CAS  Google Scholar 

  4. Steinbeck G, Andresen D, Seidl K, Brachmann J, Hoffmann E, Wojciechowski D, et al. Defibrillator implantation early after myocardial infarction. N Engl J Med. 2009;361:1427–36.

    Article  PubMed  CAS  Google Scholar 

  5. Moss AJ, Hall WJ, Cannom DS, Daubert JP, Higgins SL, Klein H, et al. Improved survival with an implanted defibrillator in patients with coronary disease at high risk for ventricular arrhythmia. Multicenter Automatic Defibrillator Implantation Trial Investigators. N Engl J Med. 1996;335:1933–40.

    Article  PubMed  CAS  Google Scholar 

  6. Bigger JT. Prophylactic use of implanted cardiac defibrillators in patients at high risk for ventricular arrhythmias after coronary-artery bypass graft surgery. Coronary Artery Bypass Graft (CABG) Patch Trial Investigators. N Engl J Med. 1997;337:1569–75.

    Article  PubMed  Google Scholar 

  7. Buxton AE, Lee KL, Fisher JD, Josephson ME, Prystowsky EN, Hafley G. A randomized study of the prevention of sudden death in patients with coronary artery disease. Multicenter Unsustained Tachycardia Trial Investigators. N Engl J Med. 1999;341:1882–90.

    Article  PubMed  CAS  Google Scholar 

  8. Bansch D. Primary prevention of sudden cardiac death in idiopathic dilated cardiomyopathy: the Cardiomyopathy Trial (CAT). Circulation. 2002;105:1453–8.

    Article  PubMed  Google Scholar 

  9. Moss AJ, Zareba W, Hall WJ, Klein H, Wilber DJ, Cannom DS, et al. Prophylactic implantation of a defibrillator in patients with myocardial infarction and reduced ejection fraction. N Engl J Med. 2002;346:877–83.

    Article  PubMed  Google Scholar 

  10. Kadish A, Dyer A, Daubert JP, Quigg R, Estes NAM, Anderson KP, et al. Prophylactic defibrillator implantation in patients with nonischemic dilated cardiomyopathy. N Engl J Med. 2004;350:2151–8.

    Article  PubMed  CAS  Google Scholar 

  11. Bardy GH, Lee KL, Mark DB, Poole JE, Packer DL, Boineau R, et al. Amiodarone or an implantable cardioverter-defibrillator for congestive heart failure. N Engl J Med. 2005;352:225–37.

    Article  PubMed  CAS  Google Scholar 

  12. A comparison of antiarrhythmic-drug therapy with implantable defibrillators in patients resuscitated from near-fatal ven­tricular arrhythmias. The Antiarrhythmics versus Implantable Defibrillators (AVID) Investigators. N Engl J Med. 1997;337:1576–83.

    Google Scholar 

  13. Kuck KH, Cappato R, Siebels J, Ruppel R. Randomized comparison of antiarrhythmic drug therapy with implantable defibrillators in patients resuscitated from cardiac arrest: the Cardiac Arrest Study Hamburg (CASH). Circulation. 2000;102:748–54.

    Article  PubMed  CAS  Google Scholar 

  14. Connolly SJ, Gent M, Roberts RS, Dorian P, Roy D, Sheldon RS, et al. Canadian implantable defibrillator study (CIDS): a randomized trial of the implantable cardioverter defibrillator against amiodarone. Circulation. 2000;101:1297–302.

    Article  PubMed  CAS  Google Scholar 

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Lubitz, S.A., Barrett, C.D. (2014). Ventricular Arrhythmias and Defibrillators. In: Gaggin, H., Januzzi, Jr., J. (eds) MGH Cardiology Board Review. Springer, London. https://doi.org/10.1007/978-1-4471-4483-0_24

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  • DOI: https://doi.org/10.1007/978-1-4471-4483-0_24

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  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-4482-3

  • Online ISBN: 978-1-4471-4483-0

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