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Pediatric Psoriasis

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Advances in Psoriasis

Abstract

Psoriasis is a chronic multi-system inflammatory condition with an autoimmune component. One-third to one-half of cases have onset in childhood. There are a variety of pediatric variant types of psoriasis, including generalized disease, that is similar to adult psoriasis, and types distinctive to childhood, including diaper involvement and pityriasis amiantacea. Pediatric psoriasis is associated with infectious triggers and exacerbation by the Koebner phenomenon. Children with psoriasis may have more of a tendency toward obesity as reflected by a large waist circumference. More extensive disease in childhood is associated with a poor quality of life. Therapeutics of pediatric psoriasis generally requires a global approach including identifying infectious triggers, addressing health risks including obesity, and psychological support. Prescription care includes application of mid-potency topical corticosteroids and/or calcipotriene, phototherapy with Narrowband UVB or excimer laser. In severe cases, cyclic prescribing of systemic agents for 6–12 months including methotrexate, cyclosporine and etanercept can aid in disease clearance with minimization of side effects.

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Authors and Affiliations

  1. Department of Internal Medicine, USF Health Morsani College of Medicine, 17 Davis Blvd Suite 308, Tampa, FL, 33606, USA

    Amber N. Pepper MD

  2. Department of Dermatology and Cutaneous Surgery, University of South Florida, 13330 USF Laurel Drive, Tampa, FL, 33647, USA

    Salma Pothiawala MD, MPH

  3. Department of Dermatology, Icahn School of Medicine at Mount Sinai, Mount Sinai Roosevelt, Mount Sinai St. Luke’s, Mount Sinai Beth Israel, 1090 Amsterdam Avenue, Suite 11D, New York, NY, 10025, USA

    Nanette B. Silverberg MD

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  1. Amber N. Pepper MD
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  2. Salma Pothiawala MD, MPH
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  1. St. Luke's -Roosevelt Hospital Center, New York, New York, USA

    Jeffrey M. Weinberg

  2. Department of Dermatology, Icahn School of Medicine, New York, New York, USA

    Mark Lebwohl

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Pepper, A.N., Pothiawala, S., Silverberg, N.B. (2014). Pediatric Psoriasis. In: Weinberg, J., Lebwohl, M. (eds) Advances in Psoriasis. Springer, London. https://doi.org/10.1007/978-1-4471-4432-8_20

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