Dysfunctional Mechanisms of Anti-inflammation in Aortic Stenosis
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Aortic valve disease is the third most common cardiovascular disease in the United States, exceeded only by hypertension and coronary artery disease. Approximately 2–7 % of the population older than 65 years has aortic stenosis , and calcific aortic stenosis is the most common indication for valve replacement. Despite its prevalence, the pathogenesis of calcific aortic stenosis is not well understood. In particular, the cellular mechanisms by which the aortic valve leaflets become calcified are unclear.
KeywordsAortic Valve Aortic Stenosis Aortic Valve Disease Aortic Valve Leaflet Calcific Aortic Stenosis
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