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Inflammatory Response in Cardiovascular Surgery

  • Kaan KayaEmail author
Chapter

Abstract

Inflammation can be described as a complex biochemical response of the body to remove the injurious stimuli and to initiate the healing process. It is known that cardiac surgery and cardiopulmonary bypass (CPB) initiate a systemic inflammatory response syndrome affecting the whole body. This inflammatory reaction may cause postoperative complications, including myocardial dysfunction, lung problems, renal and neurologic dysfunction, bleeding/clotting disorders, liver dysfunction, and multiple organ failure. The magnitude of the inflammatory reaction varies from patient to patient. The inflammatory response is related to the secretion of a large number of mediators and activation of complex body defense systems, including cytokines, vasoactive amines, proteases, reactive oxygen radicals, and the blood cells. Although the inflammatory response itself is a defense mechanism, it is responsible for all cardiovascular and other problems by activating complex body defense systems.

Keywords

Complement System Sodium Nitroprusside Extracorporeal Circulation Pulmonary Sequestration Extracorporeal Circuit 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag London 2013

Authors and Affiliations

  1. 1.Division of Cardiovascular SurgeryKavaklidere Umut HospitalAnkaraTurkey

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