Abstract
The systemic inflammatory response syndrome (SIRS) is multifaceted. In open-heart surgery, the surgical trauma is a contributor, but even more important is the use of cardiopulmonary bypass. After cardiac repair, reperfusion of the heart and lungs also contributes to the inflammatory response. The consequences of SIRS may be deleterious and sometimes even fatal. However, this is very rare in today’s routine surgery for congenital heart disease. It is obvious that all means to reduce SIRS should be undertaken because this factor contributes most to postoperative mortality and morbidity.
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Lindberg, H.L., Hoel, T.N. (2013). The Systemic Inflammatory Response Syndrome Following Cardiopulmonary Bypass in Children. In: Gabriel, E., Gabriel, S. (eds) Inflammatory Response in Cardiovascular Surgery. Springer, London. https://doi.org/10.1007/978-1-4471-4429-8_28
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