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The Neonate

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Disorders of Thrombosis and Hemostasis in Pregnancy

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Abstract

The development of the hematologic system in the neonate is a complex interplay of genetic, prenatal, intrapartum, gestational age-related, and postnatally acquired factors. Increased survival of neonates at lower limits of gestational age coupled with the dynamic changes in neonatal hematologic physiology during the transition from fetus to neonate makes diagnosis and management of disorders of neonatal hemostasis and thrombosis challenging. Thrombocytopenia is one of the commonest neonatal hematological problems encountered, but thromboembolism and coagulation defects also contribute to neonatal morbidity and mortality. This chapter will discuss the principal thrombocytopenic, thrombotic, and hemostatic disorders presenting in a neonatal population.

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Authors and Affiliations

  1. Neonatal Unit, Cambridge University Hospitals NHS Trust, Hills Road, 226, Cambridge, CB02QQ, UK

    Vidheya Venkatesh MRCP & Anna Curley MD, MRCPI

  2. NHSBT Oxford Centre, John Radcliffe Hospital, Headington Road, Oxford, OX3 9DU, UK

    Simon Stanworth DPhil, MRCP, FRCPath

Authors
  1. Vidheya Venkatesh MRCP
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  2. Anna Curley MD, MRCPI
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  3. Simon Stanworth DPhil, MRCP, FRCPath
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Corresponding author

Correspondence to Vidheya Venkatesh MRCP .

Editor information

Editors and Affiliations

  1. Aberdare Gardens 36, London, NW6 3QA, United Kingdom

    Hannah Cohen

  2. Dept. Obstetrics & Gynaecology, University College Hospital, Chenies Mews 86-96, London, WC1E 6HX, United Kingdom

    Patrick O'Brien

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© 2012 Springer-Verlag London

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Venkatesh, V., Curley, A., Stanworth, S. (2012). The Neonate. In: Cohen, H., O'Brien, P. (eds) Disorders of Thrombosis and Hemostasis in Pregnancy. Springer, London. https://doi.org/10.1007/978-1-4471-4411-3_15

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  • DOI: https://doi.org/10.1007/978-1-4471-4411-3_15

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  • Online ISBN: 978-1-4471-4411-3

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