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Postoperative Consequences of Surgical Trauma

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Abstract

Every surgical trauma is followed by unanticipated side effects such as pain and infection. A theory regarding the onset of these side effects is the surgical stress response with subsequent increased demands on the patient’s reserves and immune status. A demand on organ functions is increased following surgery and is thought to be mediated by trauma-induced endocrine and metabolic changes. To circumvent this problem and reduce surgical trauma, minimally invasive surgery has been increasingly implemented since 1989.. Since, many studies have shown the clinical short-term benefits for laparoscopic surgery over open procedures without compromising oncological outcome.

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References

  1. Jacobs M, Verdeja JC, Goldstein HS. Minimally invasive colon resection (laparoscopic colectomy). Surg Laparosc Endosc. 1991;1:144–50.

    PubMed  CAS  Google Scholar 

  2. Lacy AM, García-Valdecasas JC, Delgado S, Castells A, Taurá P, Piqué JM, Visa J. Laparoscopy-assisted colectomy versus open colectomy for treatment of non-metastatic colon cancer: a randomised trial. Lancet. 2002;359:2224–9.

    Article  PubMed  Google Scholar 

  3. Nelson H, Sargent DJ, Wieand S, Fleshman J, Anvari M, Stryker SJ, Beart RW, Hellinger M, Flanagan R, Peters W, Ota D. A comparison of laparoscopically assisted and open colectomy for colon cancer. N Engl J Med. 2004;350:2050–9.

    Article  CAS  Google Scholar 

  4. The COlon cancer Laparoscopic or Open Resection Study Group. Laparoscopic surgery versus open surgery for colon cancer: short-term outcomes of a randomised trial. Lancet Oncol. 2005;6:477–84.

    Article  PubMed  Google Scholar 

  5. Weeks JC, Nelson H, Gelber S, Sargent D, Schroeder G. Short-term quality-of-life outcomes following laparoscopic-assisted colectomy vs open colectomy for colon cancer: a randomized trial. JAMA. 2002;287:321–8.

    Article  PubMed  Google Scholar 

  6. Wu FPK, Sietses C, von Blomberg BME, van Leeuwen PAM, Meijer S, Cuesta MA. Systemic and peritoneal inflammatory response after laparoscopic or conventional colon resection in cancer patients: a prospective, randomized trial. Dis Colon Rectum. 2003;46:147–55.

    Article  PubMed  CAS  Google Scholar 

  7. Harmon GD, Senagore AJ, Kilbride MJ, Warzynski MJ. Interleukin-6 response to laparoscopic and open colectomy. Dis Colon Rectum. 1994;37:754–9.

    Article  PubMed  CAS  Google Scholar 

  8. Schwenk W, Jacobi C, Mansmann U, Bohm B, Muller JM. Inflammatory response after laparoscopic and conventional colorectal resections – results of a prospective randomized trial. Langenbeck’s Arch Surg. 2000;385:2–9.

    Article  CAS  Google Scholar 

  9. Veenhof AA, Sietses C, von Blomberg BM, Van Hoogstraten IM, vd Pas H, Meijerink WJ, vd Peet DL, vd Tol MP, Bonjer HJ, Cuesta MA. The surgical stress response and postoperative immune function after laparoscopic or conventional total mesorectal excision in rectal cancer: a randomized trial. Int J Colorectal Dis. 2011;26:53–9.

    Article  PubMed  CAS  Google Scholar 

  10. Wilmore DW, Kehlet H. Management of patients in fast track surgery. BMJ. 2001;322:473–6.

    Article  PubMed  CAS  Google Scholar 

  11. Kehlet H. Fast-track colorectal surgery. Lancet. 2008;371:791–3.

    Article  PubMed  Google Scholar 

  12. Kehlet H, Wilmore DW. Evidence-based surgical care and evolution of fast-track surgery. Ann Surg. 2008;248:189–98.

    Article  PubMed  Google Scholar 

  13. Vlug MS, Wind J, Hollmann MW. Laparoscopy in combination with fast track multimodal management is the best perioperative strategy in patients undergoing colonic surgery: a randomized clinical trial (LAFA-study). Ann Surg. 2011;254:868–75.

    Article  PubMed  Google Scholar 

  14. Veenhof AA, Vlug MS, vd Pas MH, et al. Surgical stress response and postoperative immune function after laparoscopy or open surgery with fast track or standard perioperative care; a randomized trial. Ann Surg. 2012;255:216–21.

    Article  PubMed  CAS  Google Scholar 

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Correspondence to Miguel A. Cuesta MD .

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© 2014 Springer-Verlag London

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Veenhof, A.A.F.A., Sietses, C., Cuesta, M.A. (2014). Postoperative Consequences of Surgical Trauma. In: Cuesta, M., Bonjer, H. (eds) Treatment of Postoperative Complications After Digestive Surgery. Springer, London. https://doi.org/10.1007/978-1-4471-4354-3_1

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  • DOI: https://doi.org/10.1007/978-1-4471-4354-3_1

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  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-4353-6

  • Online ISBN: 978-1-4471-4354-3

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