Abstract
It is the theme of this book that the discovery of HLA-B27 in ankylosing spondylitis in 1973, by the London and Los Angeles groups, has provided rheumatology with the possible cause of this disease, namely, commensal Klebsiella proliferation in the ileo-caecal region and ascending colon following a high intake of dietary starch.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Braun J, Brandt J, Listing J, Rudwaleit M, Sieper J. Biologic therapies in spondyloarthritis: new opportunities, new challenges. Curr Opin Rheumatol. 2003;15:394–407.
Dougados M, van der Linden S, Leirisalo-Repo M, Huitfeldt B, Juhlin R, Veys E. Sulfasalazine in the treatment of spondyloarthropathy: a randomized multi centre, double blind, placebo controlled study. Arthritis Rheum. 1995;38:618–27.
Ebringer A, Wilson C. The use of a low starch diet in the treatment of patients with ankylosing spondylitis. Clin Rheumatol. 1996;15 Suppl 1:61–5.
Feltelius N, Hvatum M, Brandtzaeg P, Knutson L, Hallgren R. Increased jejunal secretory IgA and IgM in ankylosing spondylitis: normalization after treatment with sulfasalazine. J Rheumatol. 1994;21:2076–81.
Kirwan J, Edwards A, Huitfeldt B, Thompson P, Currey H. The course of established ankylosing spondylitis and the effects of sulphasalazine over 3 years. Br J Rheumatol. 1993;32:729–33.
Kroessen S, Widmer AF, Tyndall A, Hasler B. Serious bacterial infections in patients with rheumatoid arthritis under anti-TNFα therapy. Rheumatology (Oxford). 2003;42:617–21.
Nissila M, Lahesmaa R, Leirisalo-Repo M, Lehtinen K, Toivanen P, Granfors K. Antibodies to Klebsiella pneumoniae, Escherichia coli and Proteus mirabilis in ankylosing spondylitis: effect of sulfasalazine treatment. J Rheumatol. 1994;21:2082–7.
Nissila M, Lehtinen K, Leirisalo-Repo M, Luukkainen R, Mutru O, Yli-Kerttula U. Sulfasalazine in the treatment of ankylosing spondylitis. A 26 week, placebo controlled clinical trial. Arthritis Rheum. 1988;31:111–6.
Ogrendik M. Treatment of ankylosing spondylitis with moxifloxacine. South Med J. 2007;100:366–70.
Taggart A, Gardiner P, McEvoy E, Hopkins R, Bird H. Which is the active moiety of sulfasalazine in ankylosing spondylitis? A randomized controlled study. Arthritis Rheum. 1996;39:1400–5.
Van Tubergen A, Landewe R, van der Heijde D, Hidding A, Wolter W, Ascher M. Combined spa exercise therapy is effective in patients with ankylosing spondylitis: a randomized controlled trial. Arthritis Rheum. 2001;45:430–8.
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 2013 Springer-Verlag London
About this chapter
Cite this chapter
Ebringer, A., Ebringer, A. (2013). Ankylosing Spondylitis and the ‘Low-Starch Diet’. In: Ankylosing spondylitis and Klebsiella. Springer, London. https://doi.org/10.1007/978-1-4471-4300-0_20
Download citation
DOI: https://doi.org/10.1007/978-1-4471-4300-0_20
Published:
Publisher Name: Springer, London
Print ISBN: 978-1-4471-4299-7
Online ISBN: 978-1-4471-4300-0
eBook Packages: MedicineMedicine (R0)