Abstract
Evaluation of cardiac mass or tumor has become a routine application for cardiovascular magnetic resonance (CMR) imaging. CMR is a versatile imaging modality that provides 2-dimensional or 3-dimensional imaging using a variety of pulse sequences for a comprehensive assessment of cardiac mass. Echocardiography is usually the first line imaging modality used in patients suspected of a cardiac mass or tumor; however, this technique has several limitations, is highly dependent upon availability of good echocardiographic “window” and even then may not be able to provide a comprehensive answer due to limited field of view and inability to characterize tissue. In this regard, CMR imaging has evolved as a reference standard method for the assessment of suspected cardiac tumor and is also increasingly being used for confirmation, localization, and tissue characterization of cardiac masses discovered on other types of imaging. CMR imaging readily evaluates for the presence of tumor related cardiovascular complications and is helpful in determining prognosis and treatment planning.
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References
Reynen K. Frequency of primary tumors of the heart. Am J Cardiol. 1996;77:107.
Monti L, Renifilo E, Profili M, Balzarini L. Cardiovascular magnetic resonance features of caseous calcification of the mitral annulus. J Cardiovasc Magn Reson. 2008;10:25.
Lam KY, Dickens P, Chan AC. Tumors of the heart. A 20-year experience with a review of 12,485 consecutive autopsies. Arch Pathol Lab Med. 1993;117:1027–31.
Grebench ML, Rosado-de-Christenson ML, Green CE, Burke AP, Galvin JR. Cardiac myxoma; imaging features in 83 patients. Radiographics. 2002;22:673–89.
Chiles C, Woodard PK, Gutierrez FR, et al. Metastatic involvement of the heart and pericardium: CT and MR imaging. Radiographics. 2001;21:439–49.
Molina JE, Edwards JE, Ward HB. Primary cardiac tumors: experience at the University of Minnesota. Thorac Cardiovasc Surg. 1990;38(Supple 2):183.
Ghbeis MB, Onitilo A, Greenlee R, Vidaillet H. Primary cardiac malignant tumors. Incidence, trends and survival. Circulation. 2008;118:S1098–9.
Isaacs Jr H. Fetal and neonatal cardiac tumors. Pediatr Cardiol. 2004;25:252–73.
Nadas AS, Ellison RC. Cardiac tumors in infancy. Am J Cardiol. 1968;21:363–6.
Beourkhim RS, Prakash A, Valsangiacomo Buechel ER, et al. Characterization of cardiac tumors in children by cardiovascular magnetic resonance imaging. A multicenter experience. J Am Coll Cardiol. 2011;58:1044–54.
Moss AJ, Allen HD. Moss and Adam’s heart disease in infants, children, and adolescents: including the fetus and the young adult. 7th ed. Philadelphia: Wolters Kluwer Health/Lippincott Williams & Wilkins; 2008.
Donsbeck AV, Ranchere D, Coindre JM, et al. Primary cardiac sarcomas: an immunohistochemical and grading study with long term followup of 24 cases. Histopathology. 1999;34:295–304.
Sparrow PJ, Kurian JB, Jones TR, et al. MR imaging of cardiac tumors. Radiographics. 2005;25:1255–76.
Mitchell DG, Burk Jr DL, Vinitski S, et al. The biophysical basis of tissue contrast in extracranial MR imaging. AJR. 1987;149:831–7.
Hoffmann U, Globits S, Schima W, et al. Usefulness of magnetic resonance imaging of cardiac and paracardiac masses. Am J Cardiol. 2003;92:890–5.
Weinsaft JW, Kim HW, Shah DJ, et al. Detection of left ventricular thrombus by delayed-enhancement cardiovascular magnetic resonance: prevalence and markers in patients with systolic dysfunction. J Am Coll Cardiol. 2008;52:148–57.
Kiaffas MG, Powell AJ, Geva T. Magnetic resonance imaging evaluation of cardiac tumor characteristics in infants and children. Am J Cardiol. 2002;89:1229–33.
Randhawa K, Ganeshan A, Hoey ETD. Magnetic resonance imaging of cardiac tumors: part 1, sequences, protocols and benign tumors. Curr Probl Diagn Radiol. 2011;40:158–68.
Masui T, Takahashi M, Miura K, et al. Cardiac myxoma: identification of intratumoral hemorrhage and calcification on MR images. Am J Roentgenol. 1995;164:850–2.
Gowda RM, Khan IA, Nair CK, et al. Cardiac papillary fibroelastoma: comprehensive analysis of 725 cases. Am Heart J. 2003;146:404–10.
Wintersperger BJ, Becker CR, Gulbins H, et al. Tumors of the cardiac valves: imaging findings in magnetic resonance imaging, electron beam computed tomography, and echocardiography. Eur Radiol. 2000;10:443–9.
Harding CO, Pagon RA. Incidence of tuberous sclerosis in patients with cardiac rhabdomyoma. Am J Med Genet. 1990;37:443–6.
O’Donnell DH, Abbar S, Chaithiraphan V, et al. Cardiac tumors: optimal cardiac MR sequences and spectrum of imaging appearances. AJR. 2009;193:377–87.
Yan AT, Coffey DM, Li Y, et al. Images in cardiovascular medicine. Myocardial fibroma in gorlin syndrome b cardiac magnetic resonance imaging. Circulation. 2006;114:e376–9.
Grebenc ML, de Christenson ML R, Burke AP, Green CE, Galvin JR. Primary cardiac and pericardial neoplasms: radiologic-pathologic correlation. Radiographics. 2000;20:1073–103.
Syed IS, Feng D, Harris SR, et al. MR imaging of cardiac masses. Magn Reson Imaging Clin N Am. 2008;16:137–64.
Dennig K, Lehmann G, Richter T. An angiosarcoma in the left atrium. N Engl J Med. 2000;342:443–4.
Chul HK, Jane YD, Donna C, et al. Clinicopathologic study of 24 patients with primary cardiac sarcomas: a 10-year single institution experience. Hum Pathol. 2008;39:933–8.
Di Bella G, Gaeta M, Patane L, Lentini S. Tissue characterization of a primary cardiac angiosarcoma using magnetic resonance imaging. Rev Esp Cardiol. 2010;63:1382–3.
Araoz PA, Eklund HE, Welch TJ, Breen JF. CT and MR imaging of primary cardiac malignancies. Radiographics. 1999;19:1421–34.
Anghel G, Zoli V, Petti N, et al. Primary cardiac lymphoma: report of two cases occurring in immunocompetent subjects. Leuk Lymphoma. 2004;45:781–8.
Randhawa K, Ganeshan A, Hoey ETD. Magnetic resonance imaging of cardiac tumors: part 2, malignant tumors and tumor-like conditions. Curr Probl Diagn Radiol. 2011;40:169–79.
Mansencal N, Revault-d’Allonnes L, Pelage JP, Farcot JC, Lacombe P, Dubourg O. Usefulness of contrast echocardiography for assessment of intracardiac masses. Arch Cardiovasc Dis. 2009;102:177–83.
Roberts WT, Bax JJ, Davies LC. Cardiac CT and CT coronary angiography: technology and application. Heart. 2008;94:781–92.
Rajiah P, Kanne JP, Kalahasti V, Schoenhagen P. Computed tomography of cardiac and paracardiac masses. J Cardiovasc Comput Tomogr. 2011;5:16–29.
Israel O, Keidar Z, Bar-Shalom R. Positron emission tomography in the evaluation of lymphoma. Semin Nucl Med. 2004;34:166–79.
Rao PM, Woodard PK, Patterson A, Peterson LR. Myocardial metastasis or benign brown fat? Circ Cardiovasc Imaging. 2009;2:e25–7.
Huang CY, Yu WC, Chen KC, Lin SJ. Coronary angiography of cardiac myxomas. Clin Cardiol. 2005;28:505–9.
Luna A, Ribes R, Caro P, et al. Evaluation of cardiac tumors with magnetic resonance imaging. Eur Radiol. 2005;15:1446–55.
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16.1 Electronic Supplementary Material
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Example of volumetric coverage in an axial plane. Images are acquired from the top of the heart to the diaphragm to evaluate the interatrial mass seen on echocardiography. CMR cine with SSFP sequence clearly delineates the mass involving the atrial septum which spares the fossa ovalis (images in second row). This is typical feature of lipomatous hypertrophy of interatrial septum. This was further investigated with black blood imaging with and without fat saturation which confirmed fatty nature of this pseudo-tumor (AVI 13005 kb)
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Syed, M.A., Mohiaddin, R.H. (2012). Cardiac Tumors. In: Syed, M., Mohiaddin, R. (eds) Magnetic Resonance Imaging of Congenital Heart Disease. Springer, London. https://doi.org/10.1007/978-1-4471-4267-6_16
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DOI: https://doi.org/10.1007/978-1-4471-4267-6_16
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