Sentinel Lymph Node Mapping in the Management of Cervical Cancer

  • Lukas Rob


Regional lymph node status is the most important prognostic factor for survival in patients with early cervical cancer. Pelvic lymph node dissections are routinely performed as part of standard surgical treatment. Systematic pelvic lymphadenectomy is associated with short- and long-term morbidities. The chapter discusses single components of sentinel lymph node mapping (SLNM) and results related to the detection of sentinel lymph nodes. SLNM biopsy performed by an experienced team for small volume tumors (<2 cm) has a high specific side detection rate, excellent negative predictive value and high sensitivity. Uncommon lymphatic drainage has been reported in 15 % of cervical cancer patients. There is sufficient data now to suggest that SLNM with 99mTc in combination with blue dye in the hands of a skilled, experienced surgeon should prove highly useful in individualized cervical cancer surgery and as a viable option to increase the safety of less radical fertility-sparing surgery.


Sentinel lymph node Cervical cancer Fertility-sparring surgery Individually tailored surgery 


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Copyright information

© Springer-Verlag London 2015

Authors and Affiliations

  1. 1.Department of Obstetrics and Gynecology, 2nd Medical FacultyCharles UniversityPragueCzech Republic

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