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Bone Marrow Involvement in Primary Mature B and T Cell Leukemias

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Bone Marrow Lymphoid Infiltrates

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Abstract

Mature B and T cell neoplasms evolving with a leukaemic picture often, if not always, involve the bone marrow (BM). In routine practice, BM assessment in these conditions is, as a rule, indicated. Unlike in B and T cell lymphomas (nodal or tissue based), the BM in mature lymphoid leukaemias does not provide relevant information on staging. However, its evaluation is helpful to: (i) establish and/or confirm a suspected diagnosis, (ii) estimate the haemopoietic reserve, (iii) document relapse and, (iv) assess the response and quality of response following treatment.

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Author information

Authors and Affiliations

  1. Department of Histopathology, Royal Marsden Hospital, 203 Fulham Road, London, SW3 6JJ, UK

    Ayoma D. Attygalle MBBS, Ph.D.

  2. Department of Pathology, Royal Marsden Hospital, London, UK

    Ayoma D. Attygalle MBBS, Ph.D.

  3. Department of Haemato-Oncology, Royal Marsden Hospital, 203 Fulham Road, London, SW3 6JJ, UK

    Estella Matutes M.D., Ph.D., FRCPath

  4. Institute of Cancer Research, London, UK

    Estella Matutes M.D., Ph.D., FRCPath

  5. The Royal Marsden NHS Foundation Trust, London, UK

    Estella Matutes M.D., Ph.D., FRCPath

Authors
  1. Ayoma D. Attygalle MBBS, Ph.D.
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  2. Estella Matutes M.D., Ph.D., FRCPath
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Correspondence to Ayoma D. Attygalle MBBS, Ph.D. .

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Editors and Affiliations

  1. , Department of Hematopathology, Evangelismos Hospital, Ersis Street 9, Athens, 15452, Greece

    Dimitra Anagnostou

  2. Royal Marsden Hospital, Inst. Cancer Research, NHS Foundation Trust, Fulham Road, London, SW3 6JJ, United Kingdom

    Estella Matutes

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Attygalle, A.D., Matutes, E. (2012). Bone Marrow Involvement in Primary Mature B and T Cell Leukemias. In: Anagnostou, D., Matutes, E. (eds) Bone Marrow Lymphoid Infiltrates. Springer, London. https://doi.org/10.1007/978-1-4471-4174-7_10

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  • DOI: https://doi.org/10.1007/978-1-4471-4174-7_10

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