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Fetal Liver Tissue Transplant in Alcoholic Fatty Degeneration of the Liver: A Study of 13 Cases

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Human Fetal Tissue Transplantation

Abstract

Globally, 1.4 million deaths occur annually as a result of chronic liver diseases. The reasons for this high death toll include unavailability of healthy liver donors and highly expensive liver transplantation treatment.

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References

  1. Parveen N, Aleem AK, Habeeb MA, Habibullah CM. An update on hepatic stem cells: bench to bedside. Curr Pharm Biotechnol. 2011;12(2):226–30.

    Article  PubMed  CAS  Google Scholar 

  2. Dai LJ, Li HY, Guan LX, Ritchie G, Zhou JX. The therapeutic potential of bone marrow-derived mesenchymal stem cells on hepatic cirrhosis. Stem Cell Res. 2009;2(1):16–25.

    Article  PubMed  Google Scholar 

  3. Zhao Q, Ren H, Zhu D, Han Z. Stem/progenitor cells in liver injury repair and regeneration. Biol Cell. 2009;101(10):557–71.

    PubMed  Google Scholar 

  4. Adams LA, Angulo P, Lindor KD. Nonalcoholic fatty liver disease. Can Med Assoc J. 2005;172(7):899–905. doi:10.1503/cmaj.045232.

    Article  Google Scholar 

  5. Hagihara M, Shimura T, Takebe K, Munkhbat B, Tsuji K. Effects of iso and xeno fetal liver fragments transplantation on acute and chronic liver failure in rats. Cell Transplant. 1994;3(4):283–90.

    PubMed  CAS  Google Scholar 

  6. Yrjö TK, Emilia K, Vasily S, Wagner HD, Jaakko L, Veli-Matti T, Zygmunt M. Extracellular matrix and tissue regeneration. In: Gustav S, editor. Regenerative medicine. Dordrecht: Springer; 2011. p. 21–80. doi:10.1007/978-90-481-9075-1_2. Part 1.

    Google Scholar 

  7. Kmieć Z. Cooperation of liver cells in health and disease. Adv Anat Embryol Cell Biol. 2001;161:III–XIII, 1–151.

    PubMed  Google Scholar 

  8. Méndez-Sanchez N, Chávez-Tapia NC, Uribe M. Hepatocyte transplantation for acute and chronic liver diseases. Ann Hepatol. 2005;4(3):212–5.

    PubMed  Google Scholar 

  9. Marongiu F, Gramignoli R, Dorko K, Miki T, Ranade AR, Paola Serra M, Doratiotto S, Sini M, Sharma S, Mitamura K, Sellaro TL, Tahan V, Skvorak KJ, Ellis EC, Badylak SF, Davila JC, Hines R, Laconi E, Strom SC. Hepatic differentiation of amniotic epithelial cells. Hepatology. 2011;53(5):1719–29. doi:10.1002/hep.24255.

    Article  PubMed  CAS  Google Scholar 

  10. Bhattacharya N. Fetal cell/tissue therapy in adult disease: a new horizon in regenerative ­medicine. Clin Exp Obstet Gynecol. 2004;31(3):167–73.

    PubMed  CAS  Google Scholar 

  11. Bhattacharya N. A study and followup (1999–2009) of human fetal neurotransplants at a heterotopic site outside the brain in patients of advanced Idiopathic Parkinsonism. In: Bhattacharya N, Stubblefield P, ­editors. Regenerative medicine using pregnancy-specific biological substances. London: Springer; 2011. p. 407. doi:10.1007/978-1-84882-718-9_39.

    Chapter  Google Scholar 

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Acknowledgment

The Department of Science and Technology, Government of West Bengal supported the investigator with a research grant during his tenure at Bijoygarh State Hospital from 1999 to 2006. The work started in Bijoygarh Government Hospital (1999–2006) and was followed up at Vidyasagore Government Hospital subsequently. The author gratefully acknowledges the support of the patients who volunteered for this research work. The guidance of Prof. K. L. Mukherjee (Biochemistry) and Prof. M. K. Chhetri, former Director of Health Services, is gratefully acknowledged.

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Correspondence to Niranjan Bhattacharya D.Sc., M.D., M.S., FACS (USA) .

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Bhattacharya, N. (2013). Fetal Liver Tissue Transplant in Alcoholic Fatty Degeneration of the Liver: A Study of 13 Cases. In: Bhattacharya, N., Stubblefield, P. (eds) Human Fetal Tissue Transplantation. Springer, London. https://doi.org/10.1007/978-1-4471-4171-6_28

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  • DOI: https://doi.org/10.1007/978-1-4471-4171-6_28

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  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-4170-9

  • Online ISBN: 978-1-4471-4171-6

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