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Biology of Mitral Valve Disease

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Cardiac Valvular Medicine

Abstract

Understanding the biology of the mitral valve is becoming increasing important as surgical valve repair, percutaneous techniques and potential medical therapies are becoming important in this disease process. The mitral valve’s structure, anatomy and function are quite complex making it a difficult valve lesion to treat with interventions and medical therapies. The pathology has many classifications in terms of degrees of valve severity and classification of disease pathology. As the science in the field of mitral valve biology increases so will our understanding towards treatment options for these patients. This chapter will discuss the scientific studies to date and approaches for future studies.

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Authors and Affiliations

  1. Department of Medicine, Cardiovascular Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA

    Elena Aikawa

  2. Department of Bioengineering, Rice University, Houston, TX, USA

    K. Jane Grande-Allen

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  1. Elena Aikawa
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  2. K. Jane Grande-Allen
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Correspondence to Elena Aikawa .

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Editors and Affiliations

  1. , Molecular Biology and Biochemistry, Mayo Clinic, Rochester, 55905, Minnesota, USA

    Nalini M. Rajamannan

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Aikawa, E., Grande-Allen, K.J. (2013). Biology of Mitral Valve Disease. In: Rajamannan, N. (eds) Cardiac Valvular Medicine. Springer, London. https://doi.org/10.1007/978-1-4471-4132-7_17

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