Failed Treatment of Retinal Detachment

  • W. R. Lee


This chapter serves primarily as a guide to the causative pathology and the secondary disturbances which are encountered when an enucleated eye is submitted with a clinical history of “Retinal detachment — treatment unsuccessful”. With technical advancement and a more aggressive surgical approach to trauma and diabetes, such specimens, although rare, are being submitted more frequently than in the past and will also be available via the Autopsy Service. In addition, clinicopathological correlation is more significant in view of the development of new techniques (for a comprehensive review see Glaser and Michels 1989).


Retinal Pigment Epithelium Retinal Detachment Retinal Pigment Epithelial Cell Macular Hole Outer Nuclear Layer 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. Akiba J, Quiroz MA, Trempe CL (1990) Role of posterior vitreous detachment in idiopathic macular holes. Ophthalmology 97: 1610–1613PubMedGoogle Scholar
  2. Barr CC (1990) The histopathology of successful retinal reattachment. Retina 10: 189–194PubMedGoogle Scholar
  3. Bock GR, Widdows K (1990) (eds) Myopia and the control of eye growth. Ciba Foundation Symposium 155. Wiley, ChichesterCrossRefGoogle Scholar
  4. Boldrey EE, Egbert P, Gass JDM, Friberg T (1985) The histopathology of familial exudative vitreoretinopathy. Arch Ophthalmol 103: 238–241PubMedCrossRefGoogle Scholar
  5. Carlsson EC, Bjork NJ (1990) SEM and TEM analysis of isolated human retinal microvessel membranes in diabetic retinpathy. Anat Rec 226: 295–306CrossRefGoogle Scholar
  6. Cherfan GM, Smiddy WE, Michels R et al. (1988) Clinicopathologic correlation of pigmented epiretinal membranes. Am J Ophthalmol 106: 536–545PubMedCrossRefGoogle Scholar
  7. Curtin BJ (1985) The myopias: basic science and clinical management. Harper & Row, Philadelphia, pp 3–15Google Scholar
  8. Daicker B (1978) The macular fatty degeneration of the peripheral retina. Graefe’s Arch Ophthalmol 205: 147–155CrossRefGoogle Scholar
  9. Federman JL, Eagle RC (1990) Extensive peripheral retinectomy combined with posterior 360° retinopathy for retinal re-attachment in advanced proliferative vitreoretinopathy cases. Ophthalmology 97: 1305–1320PubMedGoogle Scholar
  10. Foos RY (1978) Retinal holes. Am J Ophthalmol 86: 354–358Google Scholar
  11. Foos RY, Allen RA (1967) Retinal tears and lesser lesions of the peripheral retina in autopsy eyes. Am J Ophthalmol 64: 643–655PubMedGoogle Scholar
  12. Foos RY, Freeman SS (1970) Reticular cystoid degeneration of the peripheral retina. Am J Ophthalmol 69: 392–403PubMedGoogle Scholar
  13. Foulks GN, Hatchell DL, Proia AD, Klintworth GK (1991) Histo-pathology of silicone oil keratopathy in humans. Cornea 10: 29–37PubMedGoogle Scholar
  14. Gass JDM (1988) Idiopathic senile macular hole. Its early stages and pathogenesis. Arch Ophthalmol 106: 629–6639PubMedCrossRefGoogle Scholar
  15. Glaser BM, Michels RG (1989) (eds) Retina, vol 3. Mosby, St Louis, pp 116–151Google Scholar
  16. Glaser BM, Carter JB, Kuppermann BD, Michels RG (1991) Perfluorooctane in the treatment of giant retinal tears with proliferative vitreoretinopathy. Ophthalmology 98: 1613–1621PubMedGoogle Scholar
  17. Hui Y-N, Goodnight R, Zhang X-J, Sorgente N, Ryan S (1988) Glial epiretinal membranes and contraction. Immunohistiochemical and morphologic studies. Arch Ophthalmol 106: 1280–1285Google Scholar
  18. Kanski JJ (1975) Peripheral retinal degeneration. Trans OSUK 95: 173–177Google Scholar
  19. Marmor MF (1989) Mechanisms of normal retinal adhesion. In: Glaser BM, Michels RG (eds) Retina, vol 3. Mosby, St Louis, pp 71–87Google Scholar
  20. Mazzuca DE, Benson WE (1986) Central serous retinopathy: Variants. Sury Ophthalmol 31: 170–174CrossRefGoogle Scholar
  21. Meyer E, Kurz GH (1963) Retinal pits: a study of pathological findings in two cases. Arch Ophthalmol 70: 640–646PubMedCrossRefGoogle Scholar
  22. Morino I, Hiscott P, McKechnie N, Grierson I (1990) Variation in epiretinal membrane components with clinical duration of the proliferative tissue. Br J Ophthalmol 74: 393–399PubMedCrossRefGoogle Scholar
  23. Nakamura K, Refojo MF, Crabtree DV, Leong FL (1990) Analysis and fractionation of silicone and fluorosilicone oils for intraocular use. Invest Ophthalmol Vis Sci 31: 2059–2069PubMedGoogle Scholar
  24. Nork TM, Wallow IH, Sramek SJ, Stevens TS, De Venecia G (1990) Immunocytochemical study of an eye with proliferative vitreoretinopathy and retinal tacks. Retina 10: 78–85PubMedCrossRefGoogle Scholar
  25. Ohira A, de Juan E Jr (1990) Characterization of glial involvement in proliferative diabetic retinopathy. Ophthalmologica 201: 187–195PubMedCrossRefGoogle Scholar
  26. O’Malley PF, Allen RA, Straatsma BR, O’Malley CC (1965) Paving stone degeneration of the retina. Arch Ophthalmol 73: 169–182PubMedCrossRefGoogle Scholar
  27. O’Malley PF, Allen RA (1967) Peripheral cystoid degeneration of the retina: incidence and distribution in 1,000 autopsy cases. Arch Ophthalmol 77: 769–776PubMedCrossRefGoogle Scholar
  28. Smiddy WE, Michels RG, Green WR (1990) Morphology, pathology, and surgery of idiopathic vitreoretinal macular disorders. Retina 10: 288–296PubMedGoogle Scholar
  29. Straatsma BR, Foos RY (1973) Typical and reticular degenerative retinoschisis. Am J Ophthalmol 75: 551–575PubMedGoogle Scholar
  30. Straatsma BR, Zeegen PD, Foos RY, Feman SS, Shabo AL (1974) Lattice degeneration of the retina. Am J Ophthalmol 77: 619–649PubMedGoogle Scholar

Copyright information

© Springer-Verlag London 1993

Authors and Affiliations

  • W. R. Lee
    • 1
  1. 1.Department of PathologyUniversity of GlasgowGlasgowUK

Personalised recommendations