The stiff man syndrome (Moersch and Woltman 1956) is a disorder characterised by the gradual development of symmetrical stiffness or rigidity of axial and proximal limb muscles. The rigidity is usually associated with spasms of muscular contraction often provoked by sensory or emotional stimuli. The rigidity consists of a board-like contraction which lessens during sleep. There are no other neurological signs. Other causes of muscular rigidity, including metabolic disorders, polymyositis and chronic tetanus (McQuillen et al. 1967) must be excluded.
KeywordsCarbamazepine Auger Clonidine Myopathy Thyrotoxicosis
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