Mechanism of Thrombosis in the Antiphospholipid Syndrome: Binding to Platelets

  • J. C. Reverter
  • D. Tàssies


Antiphospholipid antibodies (aPL) are related to thrombosis in the antiphospholipid syndrome [1, 2] and numerous pathophysiological mechanisms have been suggested involving cellular effects, plasma coagulation regulatory proteins and fibrinolysis [3]. Among the mechanisms supposed to be involved, platelets have been considered as a promising potential target to circulating aPL in causing antibody-mediated thrombosis.


Systemic Lupus Erythematosus Systemic Lupus Erythematosus Patient Platelet Activation Anticardiolipin Antibody Platelet Membrane 
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  • J. C. Reverter
  • D. Tàssies

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