Abstract
The gut derives from that part of the secondary yolk sac which becomes enclosed by the head, tail and lateral folds of the embryonic plate at around the 20th day of development. The head and tail folds enclose the fore- and hindgut respectively. The intermediate portion of the intraembryonic yolk sac formed the midgut which connects through a wide communication with the extraembryonic part of the secondary yolk sac (the definitive yolk sac). This communication becomes progressively reduced by better definition of the head, tail and lateral folds of the embryo (Fig. 16.1); by 28 days the communication is via a narrow vitelline duct and the umbilical cord is clearly visible. At about this time the primitive foregut and hindgut come into contact with rostral and caudal invaginations, the stomodeum and proctodeum. Most of the epithelium and glands of the digestive tract originate from embryonic endoderm, while the epithelium of the cranial and caudal ends is derived respectively from the stomodeum and proctodeum.
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Variend, S. (1987). The Gastrointestinal Tract and Exocrine Pancreas. In: Keeling, J.W. (eds) Fetal and Neonatal Pathology. Springer, London. https://doi.org/10.1007/978-1-4471-3523-4_16
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