Abstract
It is important to realise that lung cancer is not a homogeneous entity but instead comprises a number of different histopathological groups and subgroups. A knowledge of the histopathology of lung tumours is not just of academic interest but provides a better framework for ascertaining the aetiology of a given tumour, predicting outcome and determining treatment. For example, small cell carcinoma behaves in a very different way from other types of lung cancer; it metastasises very early and is very often surgically inoperable by the time of diagnosis. On the other hand squamous cell carcinoma, if localised to the lung at operative resection, has a relatively good prognosis. The incidence of squamous cell carcinoma and small cell carcinoma is greatly increased in smokers whereas adenocarcinoma does not show as great an increase.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Adamson JS, Senior RM, Merill T (1968) Alveolar cell carcinoma: An electron microscopic study. Am Rev Respir Dis 100: 550–557.
Azzopardi JG (1959) Oat cell carcinoma of the bronchus. J Pathol Bacteriol 78: 513–519
Bensch KG, Corrin B, Pariente R, Spencer H (1968) Oat cell carcinoma of the lungs: its origin and relationship to bronchial carcinoid. Cancer 22: 1163–1172
Bolen JW, Thorning D (1982) Histogenetic classification of pulmonary carcinomas. Pathol Annu 1: 77–100
Carter D, Eggleston JC (1980) Giant cell carcinoma. In: Tumours of the lower respiratory tract. Second Series Fascicle, AFIP, Washington 17: 155–160
Churg A (1978) The fine structure of large cell undifferentiated carcinoma of the lung. Human Pathol 2: 143–156
Flanagan CP, Roeckel IE (1964) Giant cell carcinoma of the lung. Anatomical and clinical correlations. Am J Med 36: 214–221
Gibbs AR, Seal RME (1982a) Lung carcinomas. In: Gresham GA (ed) Atlas of pulmonary pathology. MTP Press, Lancaster, pp 103–110
Gibbs AR, Seal RME (1982b) Occupational lung disorders II. Silicate pneumoconioses. In: Gresham GA (ed) Atlas of pulmonary pathology. MTP Press, Lancaster, pp 91–95
Goldman KP (1965) Histology of lung cancer in relation to prognosis. Thorax 20: 298–302
Greenberg SD, Smith MN,Spjut HJ (1975) Bronchiolo-alveolar carcinoma — cell of origin. Am J Clin Pathol 63: 153–167
Harwood TR, Gracey DR, Yakoo H (1976) Pseudomesotheliomatous carcinoma of the lung. A variant of peripheral lung cancer. Am J Clin Pathol 65: 159–167
Katlic M, Carter D (1979) Prognostic implications of histology, size and location of primary tumours. In: Rozencweig M (ed) Treatment of lung cancer. Raven Press, New York, pp 143–150
Katzenstein A-A, Prioleau PG, Askin FB (1980) The histologic spectrum and significance of clear cell change in lung carcinoma. Cancer 45: 943–947
Kodama T, Shimosoto Y, Kameya T (1982) Histology and ultrastructure of bronchogenic and bronchial gland adenocarcinomas (including adenoid cystic and mucoepidermoid carcinomas) in relation to histogenesis. In: Shimosato Y, Melamed MR, Nettesheim P (eds) Morphogenesis of lung cancer, vol I. CRC Press, Boca Raton, vol I, pp 147–166
Kuhn C (1972) Fine structure of bronchiolo-alveolar carcinoma. Cancer 30: 1107–1118
Larsson S, Zettergren L (1976) Histological typing of lung cancer. Acta Pathol Microbiol Scand A] 84: 529–537
Lichtiger B, Mackay B, Tessmer CF (1970) Spindle cell variant of squamous carcinoma. A light and electron microscopic study of 13 cases. Cancer 26: 1311–1320
McDowell EM, McLaughlin JS, Mereny DK, Kieffer RF, Harris CC, Trump B (1978) The respiratory epithelium V. Histogenesis of lung carcinomas in the human. J Natl Cancer Inst 61: 587–606
Melamed MR, Zaman MB (1982) Pathogenesis of epidermoid carcinoma of lung. In: Shimosato Y, Melamed MR, Nettesheim P (eds) Morphogenesis of lung cancer, vol 1. CRC Press, Boca Raton, pp 37–64
Meyer EC, Liebow AA (1965) Relationship of interstitial pneumonia, honeycoming and atypical epithelial proliferation to cancer of the lung. Cancer 18: 322–351
Raeburn C, Spencer H (1953) A study of origin and development of lung cancer. Thorax 8: 1–10
Rubinstein I, Baum GL, Kalter Y, Pauzner Y, Lieberman Y, Bubis JJ (1979) The influence of cell type and lymph node metastases on survival of patients with carcinoma of the lung undergoing thoracotomy. Am Rev Respir Dis 119: 253–262
Shimosato Y, Kodama T, Kameya T (1982) Morphogenesis of peripheral type adenocarcinoma of the lung. In: Shimosato Y, Melamed MR, Nettesheim P (eds) Morphogenesis of lung cancer, vol 1. CRC Press, Boca Raton, pp 65–90
Sidhu GS (1982) The ultrastructure of malignant epithelial neoplasms of the lung. Pathol Annu 1: 235–266
Too LC, Delarue NC, Sanders D, Weisbrod G (1978) Bronchiolo-alveolar carcinoma: a correlative clinical and cytologic study. Cancer 42: 2759–2767
World Health Organisation (1981) Histological typing of lung tumours, 2nd edn. Geneva
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1984 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Gibbs, A.R., Seal, R.M.E. (1984). The Histological Varieties of Bronchial Carcinoma. In: Bates, M. (eds) Bronchial Carcinoma. Springer, London. https://doi.org/10.1007/978-1-4471-3516-6_9
Download citation
DOI: https://doi.org/10.1007/978-1-4471-3516-6_9
Publisher Name: Springer, London
Print ISBN: 978-1-4471-3518-0
Online ISBN: 978-1-4471-3516-6
eBook Packages: Springer Book Archive