Radiographically occult lung cancer may be defined as that situation in which a patient has sputum positive for cancer cells but a negative chest radiograph (Williams and Cortese 1982). A screening programme for lung cancer was set up in the early 1970s by the U.S. National Cancer Institute involving a collaborative study between Johns Hopkins Hospital, New York Memorial Hospital and the Mayo Clinic. Each centre aimed at enrolling about 10 000 male smokers at risk, 5000 each in the screen and control groups. The majority of the information on radiographically occult lung cancer has been generated therefrom in individual reports (Marsh et al. 1978; Melamed et al. 1981; Williams and Cortese 1982).
KeywordsLung Cancer Squamous Cell Cancer Large Cell Carcinoma Bronchial Carcinoma Sputum Cytology
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