Clinical Features of Hypermobility (Locomotor System and Extra-articular)

  • Peter Beighton
  • Rodney Grahame
  • Howard Bird


The majority of persons with lax ligaments and loose joints suffer no articular problems. For them hypermobility is a positive attribute which enables enhanced participation in a wide variety of physical activities (see Chap. 8). However not all are so fortunate, and some experience locomotor problems as a direct result of their laxity. When symptoms result, the term ‘hypermobility syndrome’ is applied (Kirk et al. 1967). It must be emphasised that this designation is non-specific and in this context it does not denote any precise disease entity. The spectrum of rheumatic complications in the hypermobility syndrome is wide and, in most cases, the pathogenesis of the presenting lesion is directly related to the articular laxity.


Carpal Tunnel Syndrome Osteogenesis Imperfecta Mitral Valve Prolapse Joint Laxity Joint Hypermobility 
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Locomotor System Complications

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Extra-articular Manifestations

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Copyright information

© Springer-Verlag Berlin Heidelberg 1983

Authors and Affiliations

  • Peter Beighton
    • 1
  • Rodney Grahame
    • 2
  • Howard Bird
    • 3
    • 4
  1. 1.MRC Research Unit for Inherited Skeletal Disorders, Medical School and Groot Schuur HospitalUniversity of Cape TownSouth Africa
  2. 2.Guy’s HospitalLondonEngland
  3. 3.University of LeedsHarrogateEngland
  4. 4.General Infirmary at Leeds and Royal Bath HospitalHarrogateEngland

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