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Placental Protein Hormones (hCG and hPL)

  • Tim Chard
  • Arnold Klopper

Abstract

The human placenta secretes a range of protein and small peptide hormones. The latter, which include corticotrophin (ACTH) and releasing factors, are only of academic interest and will not be discussed here. The larger protein hormones [human placental lactogen (hPL) ; human chorionic gonadotropin (hCG)] are the subjects of this chapter. Both are widely used in routine clinical practice, but for very different applications. Thus, hPL is a classic ‘placental function test’ in the sense of ascertaining fetal wellbeing in late pregnancy, whereas hCG is primarily employed as a ‘pregnancy test’ or for the monitoring of trophoblastic tumours. However, the applications overlap to the extent that both have been used for the monitoring of abnormalities of early pregnancy, in particular threatened abortion.

Keywords

Obstet Gynecol Early Pregnancy Corpus Luteum Late Pregnancy Placental Lactogen 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1982

Authors and Affiliations

  • Tim Chard
    • 1
  • Arnold Klopper
    • 2
  1. 1.St Bartholomew’s Hospital Medical College and the London Hospital Medical CollegeLondonUK
  2. 2.Department of Obstetrics and GynaecologyRoyal InfirmaryAberdeenUK

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