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Fluid and Electrolyte Balance

  • F. D. Thompson

Abstract

The major function of the cardiorenal system is to maintain the fluid bathing the cells at a constant composition, for it is through this pericellular fluid that O2 and nutrients are delivered and waste products of metabolism removed. The early marine vertebrates had an extracellular fluid similar to that of their salt water environment, but with evolution to fresh water and land there were various modifications, which included the development of an integument impermeable to water and modifications in renal function to allow the excretion or conservation of water and sodium according to the prevailing conditions. This chapter will outline the distribution of water and electrolytes throughout the body and the aspects of circulatory and renal physiology which are responsible for maintaining this steady state.

Keywords

Extracellular Fluid Interstitial Fluid Distal Tubule Total Body Potassium Urinary Sodium Concentration 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Alfrey AC (1976) Disorders of magnesium metabolism. 12. In: Schrier RW (ed) Renal and electrolyte disorders. Little Brown, Boston, pp. 223–242 13.Google Scholar
  2. 2.
    Belcher KH, Vetter H (1971) Radioisotopes in medical diagnosis. Butterworths, LondonGoogle Scholar
  3. 3.
    Bennett HS, Luft JH, Hampton JC (1959) Morphological 14. characteristics of vertebrate blood capillaries. Am J Physiol 196: 381–390 15.Google Scholar
  4. 4.
    Borle AB (1974) Calcium and phosphate metabolism. Annu Rev Physiol 36: 361–390 16.Google Scholar
  5. 5.
    Brenner BM, Stein JH (1978) Sodium and water homeostasis. Churchill Livingstone, New York Edinburgh 17. LondonGoogle Scholar
  6. 6.
    Christensen HN (1975) Biological transport, 2nd edn. 18. Benjamin, LondonGoogle Scholar
  7. 7.
    Edelman IS, Liebman J (1959) Anatomy of body water and electrolytes. Am J Med 27: 256–277 19.Google Scholar
  8. 8.
    Gamble JL (1958) Clinical anatomy, physiology and pathology of extracellular fluid, 7th edn. Harvard Uni- 20. versity Press, CambridgeGoogle Scholar
  9. 9.
    Gennari FJ, Cohen JL (1975) Potassium homeostasis and 21. acid base balance. Kidney Int 8: 1PubMedCrossRefGoogle Scholar
  10. 10.
    Glynn IM (1968) Membrane ATP-ase and cation transport. Br Med Bull 24: 165–169PubMedGoogle Scholar
  11. 11.
    Hodgkin AL, Horowicz P (1959) The influence of potassium and chloride ions on the membrane potential of single muscle fibres. J Physiol (Lond) 148: 127–160Google Scholar
  12. 12.
    Jamison RL, Maffly RH (1976) Osmotic concentration and dilution of urine. N Engl J Med 295: 1059PubMedCrossRefGoogle Scholar
  13. 13.
    Robinson JP, Flashner MS (1979) The ( Na + + Kt)activated ATPase enzymatic and transport properties. Biochimica et Biophysica Acta 549: 145–176Google Scholar
  14. 14.
    Ruszynâk I, Foldi M, Szabó G (1960) Lymphatics and lymph circulation. Elmsford, Pergamon, New YorkGoogle Scholar
  15. 15.
    Skelkurt EE (1976) Body water and electrolyte composition, Physiology, 4th edn. Little Brown, BostonGoogle Scholar
  16. 16.
    Stein WD (1967) The movement of molecules across cell membranes. Academic Press, New YorkGoogle Scholar
  17. 17.
    Strauss MB (1957) Body water in man. Little Brown, BostonGoogle Scholar
  18. 18.
    Verney EB (1947) Antidiuretic hormone and the factors which determine its release. Proc R Soc Lond [Biol] 135: 25–106CrossRefGoogle Scholar
  19. 19.
    Wiederhielm CA (1968) Dynamics of transcapillary fluid exchange. J Gen Physiol 52: 29–63PubMedCrossRefGoogle Scholar
  20. 20.
    Wilbrandt T, Rosenberg T (1961) The concept of carrier transport. Pharmacol Rev 13: 109–183PubMedGoogle Scholar
  21. 21.
    Wright FS (1974) Potassium transport by the renal tubule, vol 6. University Park Press, Baltimore, (Physiology Series One. Kidney and urinary tract physiology ) pp 79–105Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1983

Authors and Affiliations

  • F. D. Thompson

There are no affiliations available

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