Summary
In a dog model reproducing colonization of a vascular graft through an experimental bacteremia caused by Staphylococcus aureus, Dacron grafts were more colonized than ePTFE grafts for durations of graft function of 2 hours up to 2 months, while at 6 months the inverse trend was observed, both material being still more susceptible than normal aortas. A single injection of ceftriaxone 90 minutes before the bacteremic challenge completely prevented late graft infection.
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Leport, C., Goeau-Brissonniere, O., Lebrault, C., Péchere, JC. (1990). Experimental Bacteremic Vascular Graft Infection with Staphylococcus aureus. Comparative Colonization of Two Graft Materials and Prophylaxis of Late Infection. In: Wadström, T., Eliasson, I., Holder, I., Ljungh, Å. (eds) Pathogenesis of Wound and Biomaterial-Associated Infections. Springer, London. https://doi.org/10.1007/978-1-4471-3454-1_57
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DOI: https://doi.org/10.1007/978-1-4471-3454-1_57
Publisher Name: Springer, London
Print ISBN: 978-3-540-19596-2
Online ISBN: 978-1-4471-3454-1
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