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Pathogenesis of Wound and Biomaterial-Associated Infections pp 325–327Cite as

Adherence of Staphylococcus aureus to Hep2 Monolayers and Fibronectin

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Summary

Clinical isolates of the “epidemic” methicillin-resistant Staphy-lococcus aureus (EMRSA-1) and methicillin-susceptible Staphylococcus aureus (MSSA) were compared for their ability to bind to human epithelial cells (HEp2) and fibronectin by radiometric assays. EMRSA-1 adhered significantly less to HEp2 monolayers and to fibronectin than MSSA (P<0.01). The decreased binding capacity of this MRSA strain may be an important factor in its virulence.

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References

  1. Marples RR, Cooke EM. Current problems with methicillin-resistantStaphylococcus aureus. J Hosp Infection 11: 381 - 392, 1988.

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Authors
  1. J. Zoe Jordens
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Editors and Affiliations

  1. Department of Medical Microbiology, University of Lund, POB 117, S-22100, Lund, Sweden

    Torkel Wadström PhD (Professor) & Åsa Ljungh PhD (Assistant Professor) (Professor) &  (Assistant Professor)

  2. Department Medical Microbiology, Sölvegaten 23, S-23362, Lund, Sweden

    Ingvar Eliasson PhD

  3. Burns Institute, Shriners Hospital, Cincinnati, Ohio, USA

    Ian Holder PhD

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© 1990 Springer-Verlag London Limited

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Jordens, J.Z. (1990). Adherence of Staphylococcus aureus to Hep2 Monolayers and Fibronectin. In: Wadström, T., Eliasson, I., Holder, I., Ljungh, Å. (eds) Pathogenesis of Wound and Biomaterial-Associated Infections. Springer, London. https://doi.org/10.1007/978-1-4471-3454-1_39

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  • DOI: https://doi.org/10.1007/978-1-4471-3454-1_39

  • Publisher Name: Springer, London

  • Print ISBN: 978-3-540-19596-2

  • Online ISBN: 978-1-4471-3454-1

  • eBook Packages: Springer Book Archive

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