Adherence of Staphylococcus aureus to Hep2 Monolayers and Fibronectin
Clinical isolates of the “epidemic” methicillin-resistant Staphy-lococcus aureus (EMRSA-1) and methicillin-susceptible Staphylococcus aureus (MSSA) were compared for their ability to bind to human epithelial cells (HEp2) and fibronectin by radiometric assays. EMRSA-1 adhered significantly less to HEp2 monolayers and to fibronectin than MSSA (P<0.01). The decreased binding capacity of this MRSA strain may be an important factor in its virulence.
KeywordsAgar Pseudomonas Polypropylene Staphylococcus Methicillin
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