Adherence of Staphylococcus aureus to Hep2 Monolayers and Fibronectin
Clinical isolates of the “epidemic” methicillin-resistant Staphy-lococcus aureus (EMRSA-1) and methicillin-susceptible Staphylococcus aureus (MSSA) were compared for their ability to bind to human epithelial cells (HEp2) and fibronectin by radiometric assays. EMRSA-1 adhered significantly less to HEp2 monolayers and to fibronectin than MSSA (P<0.01). The decreased binding capacity of this MRSA strain may be an important factor in its virulence.
KeywordsStaphylococcus Aureus HEp2 Cell Human Epithelial Cell Hosp Infection Radiometric Assay
Unable to display preview. Download preview PDF.
- 3.Wadström T. Molecular aspects on pathogenesis of wound and foreign body infections due to staphylococci. Zbl Bakt Hyg A 266: 191 - 211, 1987.Google Scholar