Summary
Biosynthetic materials influence wound healing by providing a moist environment which stimulates tissue repair. It has been hypothesized that different physical properties of biosynthetic materials play a role in determining both the proliferation of pathogens under dressing and the ability of the material to provide a physical barrier against pathogens. The influence of several wound dressings on wound healing and bacterial infection was studied. In general, occlusive dressings were found to speed healing. However, they differed in their influence on bacterial proliferation and their ability to exclude bacterial pathogens from wounds.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Winter GD: Formation of scab and the rate of epithelialization of superficial wounds in the skin of domestic pig. Nature 1962; 193: 293–294.
Alvarez OM, Mertz PM, Eaglstein WH: The effect of occlusive dressings on collagen synthesis and re-epithelialization in superficial wounds. J Surg Res 35 (2): 142–48, 1981.
Eaglstein WH, Mertz PM: New method for assessing epidermal wound healing: The effect of triamcinolone acetonide and polyethylene film occlusion. J Invest Dermatol 71 (6): 382–4, 1989.
Mertz PM, Eaglstein WH: The Effect of a Semi-Occlusive Dressing on the Microbial Population in Superficial Wounds. Arch Surg 119: 287–9, 1984.
Williamson P, Kligman AM: A new method for the quantitative investigation of cutaneous bacteria. J Invest Dermatol 1965; 45: 498–503.
Marshall DA, Mertz PM, Eaglstein WH: Occlusive Dressings: Does Dressing Type Influence the Growth of Common Bacterial Pathogens? (In press)
Mertz PM, Marshall DA, Kuglar MA: The effect of povidone iodine in polyethylene oxide hydrogel dressing on multiplication of Staphylococcus aureus in partial thickness wounds. Arch Dermatol 1986; 122: 113.
Mertz PM. Alvarez OM, Smerbeck RV, Eaglstein WH: A new In Vivo Model for the Evaluation of Topical Antiseptics on Superficial Wounds. The Effect of 70% Alcohol and Povidone-lodine Solution. Arch Dermatol 1984; 120: 58–62.
Mertz PM, Marshall DA, Eaglstein WH: Occlusive wound dressings to prevent bacterial invasion and wound infection. J Am Acad Dermatol 1985; 12 (4): 6628.
May SR: Physiology, immunology and clinical efficacy on an adherent polyurethane wound dressing OpSite® In: Burn Wound Coverings. Vol. II DL Wise, Ed. CRC Press, Boca Raton, FL, 1984, pp 53–78.
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1990 Springer-Verlag London Limited
About this chapter
Cite this chapter
Mertz, P.M., Davis, S.C., Marshall, D.A., Eaglstein, W.H. (1990). Biosynthetic Dressing Materials and their Influence on Wound Healing and Infection. In: Wadström, T., Eliasson, I., Holder, I., Ljungh, Å. (eds) Pathogenesis of Wound and Biomaterial-Associated Infections. Springer, London. https://doi.org/10.1007/978-1-4471-3454-1_17
Download citation
DOI: https://doi.org/10.1007/978-1-4471-3454-1_17
Publisher Name: Springer, London
Print ISBN: 978-3-540-19596-2
Online ISBN: 978-1-4471-3454-1
eBook Packages: Springer Book Archive