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Mechanisms of Resistance to 4-Quinolones

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The 4-Quinolones: Anti Bacterial Agents in Vitro

Part of the book series: Springer Series in Applied Biology ((SSAPPL.BIOLOGY))

Abstract

With expanding clinical use of the 4-quinolone antibacterial agents, resistance to these agents has been identified (Wolfson and Hooper 1989a,b), and its mechanisms have been the subject of increasing study. In this article we review the current information on the mechanisms of bacterial resistance to 4-quinolones. Information related to the frequency of selection of 4-quinolone resistance and the possibilities of plasmid-mediated 4-quinolone resistance are covered in other chapters in this book and will not be addressed here in detail.

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Authors
  1. D. C. Hooper
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  2. J. S. Wolfson
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Editors and Affiliations

  1. Department of Biology, University of York, York, YO1 5DD, UK

    Geoff C. Crumplin

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© 1990 Springer-Verlag London Limited

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Hooper, D.C., Wolfson, J.S. (1990). Mechanisms of Resistance to 4-Quinolones. In: Crumplin, G.C. (eds) The 4-Quinolones: Anti Bacterial Agents in Vitro. Springer Series in Applied Biology. Springer, London. https://doi.org/10.1007/978-1-4471-3449-7_13

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  • DOI: https://doi.org/10.1007/978-1-4471-3449-7_13

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-3451-0

  • Online ISBN: 978-1-4471-3449-7

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