Abstract
Structural changes in the lungs elicit changes in pulmonary function. In most diffuse lung diseases, respiratory symptoms generally develop insidiously because of alterations of the elastic and/or the flow-resistive properties of the lungs. These symptoms occur concurrently with disturbances of gas exchange. Most of the time, the physiologic alterations occur concomitantly with radiologic changes, but in some cases, symptoms and physiologic disturbances may be present without evidence of radiologic alterations. Thus physiological assessment is necessary in the diagnostic evaluation and also in the management, evolution, and response to therapy of patients with diffuse lung diseases.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsPreview
Unable to display preview. Download preview PDF.
References
Quanjer H, Tammeling GJ, Cotes JE et al. (1993) Lung volumes and forced ventilatory flows. Official statement of the European Respiratory Society. Eur Respir J 6, suppl 16: 5–40.
American Thoracic Society (1995) Standardization of spirometry, 1994 update. Am J Respir Crit Care Med 152: 1107–36.
American Thoracic Society (1991) Lung function testing: selection of reference values and interpretative strategies. Am Rev Respir Dis 144: 1202–18.
Eliasson O, Degraff AC (1985) The use of criteria for reversibility and obstruction to define patient groups for bronchodilator trials. Influence of clinical diagnosis, Spirometrie, and anthropometric variables. Am Rev Respir Dis 132: 858–864.
Meslier N, Racineux JL (1991) Tests of reversibility of airflow obstruction. Eur Respir Rev 1: 34–40.
American Thoracic Society (1995) Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease. Am Rev Respir Dis 152: S77–S120.
Ferris BG (1978) Epidemiology standardization project. Am Rev Respir Dis 118: 55–88.
Hyatt RF, Okeson GC, Rodarte JR (1973) Influence of expiratory flow limitation on the pattern of lung emptying in man. J Appl Physiol 35: 411–19.
Rodarte JR, Hyatt RE, Cortese DA (1975) Influence of expiratory flow on closing capacity at low expiratory flow rates. J Appl Physiol 39: 60–5.
Guerry-Force ML, Muller NL, Wright JL et al. (1987) A comparison of bronchitis obliterans with organizing pneumonia, usual interstitial pneumonia, and small airways disease. Am Rev Respir Dis 135: 705–12.
Ries AL, Sosa G, Prewitt L et al. (1988) Restricted pulmonary function in cystic fibrosis. Chest 94: 575–9.
Bates DV (1989) Respiratory function in disease. 3rd ed. WB Saunders, Philadelphia.
Wilson AF (1985) ed. Pulmonary function testing, indications and interpretations. Grune & Stratton, Orlando, FL.
Burrows B, Knudson RJ, Quan SF et al. (1983) Respiratory disorders: a pathophysiologic approach. Year Book Medical Publishers, Chicago.
Enright PL, Hyatt RE (1987) Office spirometry: a practical guide to the selection and use of spirometers. Lea & Febiger, Philadelphia.
Bousey HA, Holtzman MJ, Shelle JR et al. (1980) Bronchial hyperreactivity. Am Rev Respir Dis 121: 389–413.
Sterk PJ, Bel EH (1991) The shape of the dose-response curve to inhaled bronchoconstrictor agents in asthma and in chronic obstructive pulmonary disease. Am Rev Respir Dis 143: 1433–7.
Lung Health Study (1992) Am Rev Respir Dis 145: 301–10.
West JB (1988) Ventilation, blood flow, and gas exchange. In: Murray JF, Nadel JA, eds. Respiratory Medicine. WB Saunders Company pp. 47–84.
Function of the respiratory tract. In: Seaton A, Seaton D, Leitch AG, Crofton & Douglas’s respiratory diseases. Blackwell Scientific Publications, Oxford, pp. 28–75.
Weisman IM, Zeballos RJ (1996) Pulmonary function testing and mechanics. In: American College of Chest Physicians (ed) 11th National ACCP Pulmonary Board Review, pp. 79–94.
Geneva International Labour Organisation (1966) Respiratory function test in pneumoconiosis. Occupational safety and health series No. 6.
West JB (1974) Respiratory physiology. Williams and Wilkins, Baltimore.
Cherniack RM (1977) Pulmonary function testing. WB Saunders, Philadelphia.
Cherniack RM, Cherniack L (1983) Respiration in health and disease. WB Saunders, Philadelphia.
Cherniack RM (1983) Pulmonary ventilation, circulation and gas exchange. Semin Respir Med 4: 197–205.
Cherniack RM (1988) Physiologie disturbances in interstitial lung disease. In: Schwarz MI, King Jr. TE, eds. Interstitial Lung Disease. BC Decker Inc. Toronto pp. 37–44.
Jackson LK, Fulmer JD (1988) Structural-functional features of the interstitial lung diseases. In: Fishman AP, ed. Pulmonary diseases and disorders. McGraw- Hill Book Company, New York pp. 739–54.
Crystal RG, Gadek JE, Ferrans VJ et al. (1981) Interstitial lung disease: current concepts of pathogenesis, staging and therapy. Am J Med 70: 542–68.
Fulmer JD, Crystal RG (1979) Interstitial lung disease. In: Simmons, DE, ed. Current Pulmonology. Volume 1. Boston, Houghton-Mifflin, Professional Publishers.
Carrington CB, Gaensler EA, Mikus JP et al. (1978) Natural history and treated course of usual and desquamative interstitial pneumonia. N Engl J Med 298: 801–9.
McCarthy D, Cherniack RM (1973) Regional ventilation-perfusion and hypoxia in cryptogenic fibrosing alveolitis. Am Rev Respir Dis 107: 200–8.
Epier GR, Saber FA, Gaensler EA (1980) Determination of severe impairment (disability) in interstitial lung disease. Am Rev Respir Dis 121: 647–59.
Fulmer JD, Roberts WC, Von Gal ER et al. (1979) Morphologic-physiologic correlates of the severity of fibrosis and degree of cellularity in idiopathic pulmonary fibrosis. J Clin Invest 63: 665–76.
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1999 Springer-Verlag London Limited
About this chapter
Cite this chapter
Bertorelli, G., Bocchino, V. (1999). Pulmonary Function Tests. In: Sperber, M. (eds) Diffuse Lung Disorders. Springer, London. https://doi.org/10.1007/978-1-4471-3440-4_4
Download citation
DOI: https://doi.org/10.1007/978-1-4471-3440-4_4
Publisher Name: Springer, London
Print ISBN: 978-1-4471-3442-8
Online ISBN: 978-1-4471-3440-4
eBook Packages: Springer Book Archive