Abstract
Diffuse pulmonary hemorrhage (DPH) is a syndrome defined by the clinical triad of hemoptysis, iron-deficiency anemia and transient diffuse acinar infiltrates on chest radiography [1–3]. Widespread damage of the alveolar-capillary lining leads to extensive hemorrhage from the pulmonary vasculature. DPH is caused by a heterogeneous group of disorders including Goodpasture’s syndrome, idiopathic pulmonary hemosiderosis, rapidly progressive glomerulonephritis, chemical-and drug-induced lung injury, coagulopathies, mitral stenosis and necrotizing pulmonary infections. This syndrome must be distinguished from localized alveolar hemorrhage with secondary spread of blood as seen with thromboembolism, chronic bronchitis, bronchiectasis, pneumonia and tumor [2].
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Lee-Chiong, T.L., Curtis, A.M., Matthay, R.A. (1999). Pulmonary Hemorrhage Syndromes. In: Sperber, M. (eds) Diffuse Lung Disorders. Springer, London. https://doi.org/10.1007/978-1-4471-3440-4_17
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DOI: https://doi.org/10.1007/978-1-4471-3440-4_17
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