Why Resect Pancreatic Cancer?

  • C. D. Johnson


Adenocarcinoma of the pancreas is the third commonest gastrointestinal cancer, after colorectal and gastric adenocarcinoma. In the UK its incidence is steady, whereas that of gastric cancer is falling (Ashton-Key et al. 1991). However, in contrast to gastric and colorectal adenocarcinoma, pancreatic tumours are rarely resectable, and when resected the disease is rarely cured. What then is the justification for resection at all?


Pancreatic Cancer Gastric Adenocarcinoma Operative Mortality Pancreatic Ductal Adenocarcinoma Pancreatic Resection 
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  1. Andren-Sandberg A, Ihse I (1983) Factors influencing survival after total pancreatectomy in patients with pancreatic cancer. Ann Surg 198: 605–610PubMedCrossRefGoogle Scholar
  2. Ashton-Key M, Hammersley S, Johnson CD (1991) Relative incidence of gastric and pancreatic cancer in England and Wales. Gut 32: A580–A581Google Scholar
  3. Braasch JW, Rossi RL, Watkins E et al. (1986) Pyloric and gastric preserving pancreatic resection. Ann Surg 204: 411–418PubMedCrossRefGoogle Scholar
  4. Bradbeer J, Johnson CD (1990) Pancreaticogastrostomy after pancreaticoduodenectomy. Ann R Coll Surg Engl 72: 266–269PubMedGoogle Scholar
  5. Chandiramini VA, Theis BA, Rüssel RCG (1990) Role of resection in the management of pancreatic cancers. Gut 31: A488Google Scholar
  6. Cooper MJ, Williamson RCN (1985) Conservative pancreatectomy. Br J Surg 72: 801–803PubMedCrossRefGoogle Scholar
  7. Cooper MJ, Williamson RCN, Benjamin IS et al. (1987) Total pancreatectomy for chronic pancreatitis. Br J Surg 74: 912–915PubMedCrossRefGoogle Scholar
  8. Crist DW, Sitzmann JV, Cameron JL (1987) Improved hospital morbidity, mortality and survival after the Whipple procedure. Ann Surg 206: 358–373PubMedCrossRefGoogle Scholar
  9. Dunn E (1987) The impact of technology and improved perioperative management upon survival from carcinoma of the pancreas. Surg Gynecol Obstet 164: 237–244PubMedGoogle Scholar
  10. Edis AJ, Kieman PD, Taylor WF (1980) Attempted resection of ductal carcinoma of the pancreas. Review of Mayo Clinic Experience 1951–75. Mayo Clin Proc 55: 531–536PubMedGoogle Scholar
  11. Gall FP (1987) Chronische pancreatitis: Chirugische therapie durch resections verfahren. Langenbecks Arch Chir 372: 363–368PubMedCrossRefGoogle Scholar
  12. Gastrointestinal Tumour Study Group (1987) Further evidence of effective adjuvant combined radiation and chemotherapy following curative resection of pancreatic cancer. Cancer 59: 2006–2010CrossRefGoogle Scholar
  13. Grace PA, Pitt HA, Longmire WP (1986) Pancreatoduodenectomy with pylorus preservation for adenocarcinoma of the head of the pancreas. Br J Surg 73: 647–650PubMedCrossRefGoogle Scholar
  14. Gudjunsson B, Livstone E, Spiro H (1978) Pancreatic cancer: diagnostic accuracy and survival statistics. Cancer 42: 2454–2506Google Scholar
  15. Ishikawa O, Ohigashi H, Sasaki Y et al. (1988) Practical usefulness of lymphatic and connective tissue clearance for carcinoma of the pancreas head. Ann Surg 208: 215–219PubMedCrossRefGoogle Scholar
  16. Jones BA, Langer B, Taylor BR, Girotti M (1985) Periampullary tumours. Which ones should be resected? Am J Surg 149: 46–52PubMedCrossRefGoogle Scholar
  17. Kairaluoma MI, Kiviniemi H, Stahlberg M (1987) Pancreatic resection for carcinoma of the pancreas and periampullary region in patients over 70 years of age. Br J Surg 74: 116–118PubMedCrossRefGoogle Scholar
  18. Lygidakis NJ, van der Hyde MN, Houthoff HJ et al. (1989) Resectional surgical procedures for carcinoma of the head of the pancreas. Surg Gynecol Obstet 168: 157–165PubMedGoogle Scholar
  19. Moosa AR (1982) Pancreatic cancer. Approach to diagnosis, selection for surgery and choice of operation. Cancer 50: 2689–2698Google Scholar
  20. Pellegrini CA, Heck CF, Roper et al. (1989) An analysis of the reduced morbidity and mortality rates after pancreaticoduodenectomy. Arch Surg 124: 778–781PubMedCrossRefGoogle Scholar
  21. Sato T, Saitch Y, Noto N, Matsuno S (1977) Followup studies of radical resection for pancreaticoduodenal cancer. Ann Surg 186: 581–588PubMedCrossRefGoogle Scholar
  22. Tashiro S, Mirata E, Hiraoka T et al. (1987) New techniques for pancreaticojejunostomy using a biological adhesive. Br J Surg 74: 392–394PubMedCrossRefGoogle Scholar
  23. Trede M (1987) Treatment of pancreatic carcinoma: the surgeon’s dilemma. Br J Surg 74: 79–80PubMedCrossRefGoogle Scholar
  24. Trede M, Schwall G, Saeger HD (1990) Survival after pancreatoduodenectomy: 118 consecutive resections without operative mortality. Ann Surg 211: 447–458PubMedCrossRefGoogle Scholar
  25. Tsuchiya R, Noda T, Harada N et al. (1986) Collective review of small carcinomas of the pancreas. Ann Surg 203: 77–81PubMedCrossRefGoogle Scholar
  26. Van Heerden J A (1984) Pancreatic resection for carcinoma of the pancreas: Whipple versus total pancreatectomy — an institutional persective. World J Surg 8: 880–888PubMedCrossRefGoogle Scholar

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© Springer-Verlag London Limited 1991

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  • C. D. Johnson

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