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Pancreatic Disease pp 3–17Cite as

Pathophysiology of Obstructive Jaundice

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Abstract

Specific problems may result from obstructive jaundice complicating pancreatic disease, and this is reflected in a higher mortality when surgery is performed in the presence of jaundice. This was recognised by Whipple in 1935 who recommended an initial cholecystogastrostomy to relieve jaundice prior to a pancreatic resection. The main consequences of obstructive jaundice, the underlying pathophysiological factors and possible therapies are shown in Table 1.

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  1. J. Pain
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Editors and Affiliations

  1. Faculty of Medicine, University Surgical Unit, Southampton General Hospital, Tremona Road, SO1 6HU, Southampton, UK

    C. D. Johnson MChir, FRCS (Senior Lecturer and Honorary Consultant Surgeon) (Senior Lecturer and Honorary Consultant Surgeon)

  2. Surgical Unit, Royal Infirmary, G4 OSF, Glasgow, UK

    C. W. Imrie ChB, FRCS (Consultant Surgeon) (Consultant Surgeon)

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© 1991 Springer-Verlag London Limited

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Pain, J. (1991). Pathophysiology of Obstructive Jaundice. In: Johnson, C.D., Imrie, C.W. (eds) Pancreatic Disease. Springer, London. https://doi.org/10.1007/978-1-4471-3356-8_1

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  • DOI: https://doi.org/10.1007/978-1-4471-3356-8_1

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