Endocrinology of Male Infertility and Fertility

Part of the Clinical Practice in Urology book series (PRACTICE UROLOG)


The gonads are unique amongst endocrine glands in that they have two functions: steroid hormone synthesis and gamete production. Spermatogenesis takes place within the seminiferous tubules while the sex steroids are synthesised in the Leydig cells in the interstitial spaces. As well as anatomical proximity (Fig. 6.1) there is close functional interrelationship. It has recently become clear that high intratesticular androgen concentrations are necessary for normal spermatogenesis and this concept has influenced thinking about patient management and also determined the direction of recent research.


Luteinising Hormone Sertoli Cell Leydig Cell Seminiferous Tubule Male Infertility 
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© Springer-Verlag Berlin Heidelberg 1983

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  • F. Wu

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