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Muscle and Peripheral Nerve

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Paediatric Pathology
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Abstract

The development of new techniques for the histological study of muscle and peripheral nerve has led to fresh concepts of the pathogenesis and classification of these disorders, and to a more rational and hopeful approach to both diagnosis and treatment. Naturally, new problems and controversies have also arisen.

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References

  • Afifi AK, Smith JW, Zellweger H (1965) Congenital nonprogressive myopathy, Central core and nemaline myopathy in one family. Neurology (Minneap) 15: 371

    CAS  Google Scholar 

  • Allen DE, Johnson AG, Woolf AL (1969) The intramuscular nerve endings in dystrophia myotonica, A biopsy study by vital staining and electron microscopy. J Anat 105: 1

    PubMed  CAS  Google Scholar 

  • Argov Z, Mastaglia FL (1979) Drug-induced peripheral neuropathies. Br Med J is 663

    Google Scholar 

  • Armstrong RM, Königsberger R, Mellinger J, Lovelace RE (1971) Central core disease with congenital hip dislocation, A study of two families. Neurology (Minneap) 21: 369

    CAS  Google Scholar 

  • Arnason BGW (1975) Inflammatory polyradiculoneuritis. In: Dyck PJ, Thomas PK, Lambert EH (eds) Peripheral neuropathy, vol 2. Saunders, London Philadelphia, p 1110

    Google Scholar 

  • Asbury AK (1973) Renaut bodies, A forgotten endoneurial structure. J Neuropathol Exp Neurol 32: 334

    Article  PubMed  CAS  Google Scholar 

  • Bank WJ, DiMauro S, Bonilla E, Capcizzi DM, Rowland LP (1975) A disorder of lipid metabolism and myoglobinuria. N Engl J Med 292: 443

    Article  PubMed  CAS  Google Scholar 

  • Banker BQ (1975) Dermatomyositis of childhood, Ultrastructural alterations of muscle and intramuscular blood vessels. J Neuropathol Exp Neurol 34: 46

    Article  PubMed  CAS  Google Scholar 

  • Banker BQ, Victor M (1966) Dermatomyositis (systemic angiopathy) of childhood. Medicine (Baltimore) 45: 261

    Article  CAS  Google Scholar 

  • Barbeau A (1966) The syndrome of hereditary late-onset ptosis and dysphagia in French Canada. In: Kuhn E (ed) Symposium über progressive Muskeldystrophie. Springer, Berlin, p 102

    Google Scholar 

  • Barchi RL (1975) Myotonia: An evaluation of the chloride hypothesis. Arch Neurol 32: 175

    Article  PubMed  CAS  Google Scholar 

  • Becker PE (1962) Two new families of benign sex-linked recessive muscular dystrophy. Rev Can Biol 21: 551

    PubMed  CAS  Google Scholar 

  • Behan PO, Simpson JA, Dick (1973) Immune response genes in myasthenia gravis. Lancet 2: 1033

    Google Scholar 

  • Bell CD, Conen PE (1968) Histopathological changes in Duchenne muscular dystrophy. J Neurol Sci 7: 529

    Article  PubMed  CAS  Google Scholar 

  • Berenberg RA, Pollock JM, DiMauro S, Schotland DL, Bonilla E, Eastwood A, Hays A, Vicale CT, Behrens M, Chutarian A, Rowland LP (1977) Lumping or splitting? Ophthalmoplegia plus or Kearns—Sayre syndrome. Ann Neurol 1: 37

    Article  PubMed  CAS  Google Scholar 

  • Bethlem J, van Gool J, Hülsmann WC, Meijer AEFH (1966) Familial non-progressive myopathy with muscle cramps after exercise, A new disease associated with cores in the muscle fibres. Brain 89: 569

    Article  PubMed  CAS  Google Scholar 

  • Bethlem J, Meijer AEFH, Schellens JPM, Uvran JJ (1968) Centronuclear myopathy. Eur Neurol 1: 325

    Article  PubMed  CAS  Google Scholar 

  • Bethlem J, van Wijngaarden GK, Meijer AEFH, Hülsmann WC (1969) Neuromuscular disease with type 1 fibre atrophy, central nuclei and myotube-like structures. Neurology (Minneap) 19: 705

    CAS  Google Scholar 

  • Bischoff A (1975) Neuropathy in leucodystrophies. In: Dyck PJ, Lambert EH, Thomas PK (eds) Peripheral neuropathy. Saunders, London Philadelphia, p 891

    Google Scholar 

  • Bohan A, Peter JB (1975) Polymyositis and dermatomyositis. N Engl J Med 292: 344 and 403

    Google Scholar 

  • Bradley WG (1969) Ultrastructural changes in adynamia episodica hereditaria and normokalaemic periodic paralysis. Brain 92: 379

    Article  PubMed  CAS  Google Scholar 

  • Bradley WG, Jones MZ, Mussini J-M, Fawcett PRW (1978) Becker-type muscular dystrophy. Muscle Nerve 1: 111

    Article  PubMed  CAS  Google Scholar 

  • Brooke MH (1966) The histological reaction of muscle to disease. In: Buskey EJ, Cassens R, Trautman J (eds) The physiology and biochemistry of muscle as a food. University of Wisconsin Press, Madison, p 151

    Google Scholar 

  • Brooke MH, Kaiser KK (1970) Muscle fibre types, How many and what kind? Arch Neurol 23: 369

    Article  PubMed  CAS  Google Scholar 

  • Brooke MH (1973) A neuromuscular disease characterised by fibre type disproportion. In: Kakulas PA (ed) Clinical studies in myology. Excerpta Medica, Amsterdam, p 147 (ICS no. 295 )

    Google Scholar 

  • Brooke MH, Engel WK (1966) The histologic diagnosis of neuromuscular diseases, A review of 79 biopsies. Arch Phys Med Rehabil 47: 99

    PubMed  CAS  Google Scholar 

  • Brooke MH, Engel WK (1969a) The histographic analysis of human muscle biopsies with regard to fibre types 1. Adult male and female. Neurology (Minneap) 19: 221

    CAS  Google Scholar 

  • Brooke MH, Engel WK (1969b) The histographic analysis of human muscle biopsies with regard to fibre types, 4 children’s biopsies. Neurology (Minneap) 19: 591

    CAS  Google Scholar 

  • Brownell B, Oppenheimer DR, Spalding JMK (1972) Neurogenic muscle atrophy in myasthenia gravis. J Neurol Neurosurg Psychiatry 34: 311

    Article  Google Scholar 

  • Brunberg JA, McCormick WF, Schochet SS Jr (1971) Type 3 glycogenosis: An adult with diffuse weakness and muscle wasting. Arch Neurol 25: 171

    Google Scholar 

  • Bundey S (1972) Genetic study of infantile and juvenile myasthenia gravis. J Neurol Neurosurg Psychiatry 35: 41

    Article  PubMed  CAS  Google Scholar 

  • Bundey S, Carter CO, Soothill JF (1970) Early recognition of heterozygotes for the gene of dystrophia myotonica. J Neurol Neurosurg Psychiatry 33: 279

    Article  PubMed  CAS  Google Scholar 

  • Carpenter S, Karpati G, Rothman S, Watters G (1976) The childhood type of dermatomyositis. Neurology (Minneap) 26: 952

    CAS  Google Scholar 

  • Cavanagh JB (1964) The significance of the `dying back’ process in experimental and human neurological disease. Int Rev Exp Pathol 7: 219

    Google Scholar 

  • Cavanagh JB, Mellick RS (1965) On the nature of the peripheral nerve lesions associated with acute intermittent perphyria. J Neurol Neurosurg Psychiatry 28: 320

    Article  PubMed  CAS  Google Scholar 

  • Cazzato G (1970) Myopathie changes in denervated muscle: A study of biopsy material in various neuromuscular diseases. In: Walton JN, Canal N, Scarlato G (eds) Muscle disease. Excerpta Medica, Amsterdam, p 392 (ICS no. 199 )

    Google Scholar 

  • Cheah JS, Tock EPC, Tan Sp (1975) The light and electron microscopic changes in the skeletal muscles during paralysis in thyrotoxic periodic paralysis. Am J Med Sci 269: 365

    Article  PubMed  CAS  Google Scholar 

  • Chou SM (1968) Myxovirus-like structures and accompanying nuclear changes in chronic polymyositis. Arch Pathol 86: 649

    PubMed  CAS  Google Scholar 

  • Chou SM, Gutmann L (1970) Picornavirus-like crystals in subacute polymyositis. Neurol (Minneap) 20: 205

    CAS  Google Scholar 

  • Cochrane RG, Davey TF (eds) (1964) Leprosy in theory and practice, 2nd edn. Wright, Bristol

    Google Scholar 

  • Cöers C (1975) Motor innervation of myasthenic muscles related to age. Lancet 2: 55

    Google Scholar 

  • Cöers C, Desmedt JE (1959) Mise en évidence d’une malformation caracteristique de la jonction neuromusculare dans la myasthenie. Acta Neurol Belg 59: 539

    Google Scholar 

  • Cöers C, Telerman-Toppet N (1976) Morphological and histological changes of motor units in myasthenia. Ann NY Acad Sci 274: 6

    Article  PubMed  Google Scholar 

  • Cöers C, Woolf AL (1953) The innervation of muscle. Blackwell, Oxford

    Google Scholar 

  • Cook CD, Rosen FS, Banker BQ (1963) Dermatomyositis and focal scleroderma. Pediatr Clin North Am 10: 979

    PubMed  CAS  Google Scholar 

  • Conomy JP, Levinsohn M, Fanaroff A (1975) Familial infantile myasthenia gravis: A cause of sudden death in young children. J Pediatr 87: 428

    Google Scholar 

  • Crews J, Kaiser KK, Brooke MH (1976) Muscle pathology of myotonia congenita. J Neurol Sci 28: 449

    Article  PubMed  CAS  Google Scholar 

  • Currie S, Naronha M, Harriman DGF (1974) `Minicore’ disease (Abstract). Third International Congress on Muscle Disease. Excerpta Medica, Amsterdam, p 12 (ICS no. 334)

    Google Scholar 

  • Davidenkow S (1939) Scapulo-peroneal amyotrophy. Arch Neurol 41: 694

    Google Scholar 

  • Dawkins RL, Mastaglia FL (1973) Cell-mediated cytotoxicity muscle in polymyositis. N Engl J Med 288: 434

    Article  PubMed  CAS  Google Scholar 

  • Drachman DA (1968) Ophthalmoplegia plus The neurodegenerative disorders associated with progressive external ophthalmoplegia. Arch Neurol 18: 654

    Article  PubMed  CAS  Google Scholar 

  • Drachman DB, Angus CW, Adams RN, Michelson JD, Hoffman GJ (1978) Myasthenic antibodies cross-link acetylcholine receptors to accelerate degradation. N Engl J Med 298: 1116

    Article  PubMed  CAS  Google Scholar 

  • Drachman DB, Murphy SR, Nigam MP, Hills JR (1967) `Myopathie’ changes in chronically denervated muscle. Arch Neurol 16: 14

    Google Scholar 

  • Dreyfus JS, Shapiro G Demos J (1960) Etude de la creatinekinase serique chez les myopathies et leur familles. Revue Française d’Etudes Cliniques et Biologiques 5: 384

    CAS  Google Scholar 

  • Dubowitz V (1978) Muscle disorders in childhood. In: Major problems in clinical pediatrics, vol XVI. Saunders, London

    Google Scholar 

  • Dubowitz V, Brooke MH (1973) Muscle biopsy A modern approach. Saunders, London

    Google Scholar 

  • Dubowitz V, Roy S (1970) Central core disease of muscle, Clinical histochemical and electron microscopal studies of an affected mother and child. Brain 93: 133

    Article  PubMed  CAS  Google Scholar 

  • Dunn HG, Lake BD, Dolman CL, Wilson J (1969) The neuropathy of Krabbe’s infantile cerebral sclerosis (globoid cell leucodystrophy). Brain 92: 329

    Article  PubMed  CAS  Google Scholar 

  • Dyck PJ (1966) Histologic measurements and fine structure of biopsied sural nerve, Normal and in peroneal muscular atrophy, hypertrophie neuropathy and congenital sensory neuropathy. Mayo Clin Proc 41: 742

    PubMed  CAS  Google Scholar 

  • Dyck PJ (1975) Pathologic alterations of the peripheral nervous system of man. In: Dyck PJ, Thomas PK, Lambert EH (eds) Peripheral neuropathy. Saunders, London Philadelphia p 296

    Google Scholar 

  • Dyck PJ, Lambert EH (1968a) Lower motor and primary sensory neuron diseases with peroneal muscular atrophy I. Neurologic, genetic and electrophysiologic findings in hereditary polyneuropathies. Arch Neurol 18: 603

    Google Scholar 

  • Dyck PJ, Lambert EH (1968b) Lower motor and primary sensory neuron diseases with peroneal muscular atrophy Il. Neurologic, genetic and electrophysiologic findings in various neuronal degenerations. Arch Neurol 18: 619

    Google Scholar 

  • Dyck Pi, Lambert EH, Thomas PK (1975) Peripheral neuropathy (2 vols). Saunders, London Philadelphia

    Google Scholar 

  • Edstrom L, Kugelberg E (1968) Histochemical composition, distribution of fibres and fatiguability of single motor units Anterior tibial muscle of the rat. J Neurol Neurosurg Psychiatry 31: 424

    Article  PubMed  CAS  Google Scholar 

  • Ellis FR, Kearney NP, Harriman DGF (1973) Histopathological and neuropharmacological aspects of malignant hyperpyrexia. Proc R Soc Med 66: 60

    Google Scholar 

  • Emery AEH, Smith CAB, Sanger R (1969) The linkage reactions of the loci for benign ( Becker type) X-borne muscular dystrophy, colour blindness and the Xg blood groups. Ann Hum Genet 32: 261

    Article  PubMed  CAS  Google Scholar 

  • Engel AG (1970a) Acid maltase deficiency in adults: Studies in four cases of syndrome which may mimic muscular dystrophy or other myopathies. Brain 93: 599

    Article  PubMed  CAS  Google Scholar 

  • Engel AG (1970b) Evolution and content of vacuoles in primary hypokalaemic periodic paralysis. Mayo Clin Proc 45: 774

    PubMed  CAS  Google Scholar 

  • Engel AG, Angelini C, Gomez MR (1972) Finger-print body myopathy. Mayo Clin Proc 47: 377

    PubMed  CAS  Google Scholar 

  • Engel AG, Gomez MR, Seybold ME, Lambert EH (1973) The spectrum and diagnosis of acid maltase deficiency. Neurology (Minneap) 23: 95

    CAS  Google Scholar 

  • Engel AG, Lindstrom JM, Lambert EH, Lennon VA (1977) Ultrastructural localization of the acetylcholine receptor in myasthenia gravis and its experimental autoimmune model. Neurology (Minneap) 27: 307

    CAS  Google Scholar 

  • Engel AG, Mokri B, Jerusalem F, Sakakibara H, Paulson OB (1977) Ultrastructural clues in Duchenne dystrophy. In: Rowland CP (ed) Pathogenesis of human muscular dystrophies. Excerpta Medica, Amsterdam, p 310 (ICS no 404 )

    Google Scholar 

  • Engel WK (1961) Muscle target fibres, a newly recognised sign of denervation. Nature 191: 389

    Article  PubMed  CAS  Google Scholar 

  • Engel WK (1965) Muscle biopsy. Clin Orthop 39: 80

    CAS  Google Scholar 

  • Engel WK (1970) Selective and non-selective susceptibility of muscle fibre types, A new approach to human neuromuscular disease. Arch Neurol 22: 97

    Article  PubMed  CAS  Google Scholar 

  • Engel WK (1971) `Ragged-red fibres’ in opthalmoplegia syndromes and their differential diagnosis. In: Abstract. Second International Congress on Muscle Diseases. Excerpta Medica, Amsterdam, p 28 (ICS no. 237)

    Google Scholar 

  • Engel WK, Brooke MH (1966) Histochemistry of the myotonic disorders. In: Kuhn E (ed) Progressive Muskeldystrophie, Myotonie, Myästhenia. Springer, Berlin Heidelberg New York, p. 203

    Google Scholar 

  • Engel WK, McFarlin De (1966) Discussion. Ann NY Acad Sci 135: 68

    Article  CAS  Google Scholar 

  • Engel WK, Resnick JS (1966) Late-onset rod myopathy: A newly recognised, acquired and progressive disease. Neurology (Minneap) 16: 308

    Google Scholar 

  • Engel WK, Brooke MH, Nelson PG (1966) Histochemical studies of denervated or tenotomized cat muscle, illustrating difficulties in relating experimental animal conditions to human neuromuscular diseases. Ann NY Acad Sci 138: 160

    Article  PubMed  CAS  Google Scholar 

  • Famborough D, Drachman DB, Satyamart S (1973) Neuromuscular junction in myasthenia gravis: Decreased acetylcholine receptors. Science 182: 293

    Google Scholar 

  • Fardeau M, Harpey J-P, Caille B (1975) Disproportion congénitales des différentes types de fibre musculaire avec petitesse relative des fibres de type 1, Documents morphologiques concernant les biopsies musculaires prélevées chez trois membres d’une même famille. Rev Neurol (Paris) 131: 745

    Google Scholar 

  • Fenichel GM, Shy GM (1963) Muscle biopsy experience in myasthenia gravis. Arch Neurol 9: 237

    Google Scholar 

  • Fried K, Emery AEH (1971) Spinal muscular atrophy Type II A separate genetic and clinical entity from type 1 (WerdnigHoffman disease) and type III ( Kugelberg—Welander disease ). Clin Genet 2: 203

    Article  PubMed  CAS  Google Scholar 

  • Gamstorp I (1956) Adynamia episodica hereditaria. Acta Paediatr 108: 1

    Google Scholar 

  • Gardner Medwin D, Walton JN (1974) Clinical examination of voluntary muscles In: Walton JN (ed) Disorders of voluntary muscle, 3rd edn. Churchill Livingstone, London, p 546

    Google Scholar 

  • Gauthier GF (1976) The motor end-plate: Structure. In: Landen DN (ed) The peripheral nerve. Chapman & Hall, London, p 464

    Google Scholar 

  • Goebel HH, Lenard HG, Kohlschütter A, Pilz H (1977) The ultrastructure of the sural nerve in Pompe’s disease. Ann Neurol 2: 111

    Article  Google Scholar 

  • Gonatas NK, Shy GM, Godfrey EH (1966) Nemaline myopathy, The origin of nemaline structures. N Engl J Med 274: 535

    Article  PubMed  CAS  Google Scholar 

  • Greenbaum D, Richardson PC, Salmon MV, Urich H (1964) Pathological observations in six cases of diabetic neuropathy. Brain 87: 201

    Article  PubMed  CAS  Google Scholar 

  • Guillain G, Barré JA, Strohl A (1916) Sur un syndrome de radiculo-névrite avec hyperalbuminose du liquide céphalorachidien sans un réaction cellulaire Remarques sur les caractères cliniques et graphiques des reflexes tendineux. Bulletin Societé Medicale des Hôpitaux de Paris 10: 146

    Google Scholar 

  • Gutretcht JA, Dyck PJ (1966) Segmental demyelinization in peroneal muscular atrophy nerve fibres teased from sural nerve biopsy specimens. Mayo Clin Proc 41: 775

    Google Scholar 

  • Haase GR, Shy GM (1960) Pathological changes in muscle biopsies from patients with peroneal muscular atrophy. Brain 83: 631

    Article  PubMed  CAS  Google Scholar 

  • Hall-Craggs ECB (1972) The liquificance of longitudinal fibre division in skeletal muscle. J Neurol Sci 15: 27

    Article  PubMed  CAS  Google Scholar 

  • Harper PS (1975) Congenital myotonic dystrophy in Britain, 1. Clinical aspects. 2. Genetic aspects. Arch Dis Child 50: 505 514

    Article  PubMed  CAS  Google Scholar 

  • Harriman DGF (1961) Histology of the motor end plate (motor point muscle biopsy). In: Licht S (ed) Electrodiagnosis and electromyography, 2nd edn. Licht, New Haven, p 134

    Google Scholar 

  • Harriman DGF (1976) Diseases of muscle. In: Blackwood W, Corsellis JAN (eds) Greenfield’s neuropathology. Arnold, London, p 849

    Google Scholar 

  • Hierons R (1957) Changes in the nervous system in acute perphyria. Brain 80: 176

    Article  PubMed  CAS  Google Scholar 

  • Hopkins IJ, Lindsey JR, Ford FR (1966) Nemaline myopathy A long-term clinicopathologic study of affected mother and daughter. Brain 89: 299

    Article  PubMed  CAS  Google Scholar 

  • Howes EL Jr, Price HM, Blumberg JM (1966) Hypokalaemic periodic paralysis Electron microscopic changes in the sarcoplasm. Neurology (Minneap) 16: 242

    Google Scholar 

  • Illingworth B, Cori GT, Cori CF (1956) Amylo 1,6 glucosidase in muscle tissue in generalized glycogen storage disease. J Biol Chem 218: 123

    PubMed  CAS  Google Scholar 

  • Isaacs H, Barlow MB (1970) Malignant hyperpyrexia during anaesthesia: Possible association with subclinical myopathy. Br Med J i: 295

    Article  Google Scholar 

  • James NT (1971) The distribution of muscle fibre types in fasciculi and their analysis. J Anat 110: 335

    PubMed  CAS  Google Scholar 

  • Jerusalem F, Rakuska M, Engel AG, MacDonald PD (1974) Morphometric analysis of skeletal muscle capillary ultra-structure in inflammatory myopathies. J Neurol Sci 23: 391

    Article  PubMed  CAS  Google Scholar 

  • Johnson MA, Polgar J, Weightman D, Appleton D (1973) Data on the distribution of fibre types in thirty six human muscles, An autopsy study. J Neurol Sci 18: 111

    Article  PubMed  CAS  Google Scholar 

  • Joosten E, Gabreëls F, Bagreels-Festen A, Vrensen G, Karten J, Notermans S (1974) Electron microscopic heterogeneity of onion-bulb neuropathies of the Déjerine—Sottas type Two patients in one family with the variant described by Lyon. Acta Neuropathol (Berl) 27: 105

    Article  CAS  Google Scholar 

  • Kaeser HE (1965) Scapuloperoneal muscular dystrophy. Brain 88: 407

    Article  PubMed  CAS  Google Scholar 

  • Kamensky E, Philippart M, Cancilla P, Frommes SP (1973) Cultured skin fibroblasts in storage disorders An analysis of ultrastructural features. Am J Pathol 73: 59

    PubMed  CAS  Google Scholar 

  • Karch S, Urich H (1975) Infantile polyneuropathy with defective myelination: An autopsy study Dev Med Child Neurol 17: 504

    CAS  Google Scholar 

  • Karpati G, Carpenter S, Engel AG, Watters G, Allen J, Rothman S, Klassen G, Mamer OA (1975) The syndrome of systemic carnitine deficiency. Neurology (Minneap) 25: 16

    CAS  Google Scholar 

  • Kearns TP, Sayre GP (1958) Retinitis pigmentosa, external ophthalmoplegia and complete heart block. Arch Ophthalmol 60: 280

    Article  CAS  Google Scholar 

  • Keesey J, Lindstrom J, Cokely H, Herrmann C Jr (1977) Anti-acetylcholine receptor antibody in neonatal myasthenia gravis. N Engl J Med 296: 55

    PubMed  CAS  Google Scholar 

  • Kiloh LG, Nevin S (1951) Progressive dystrophy of the external ocular muscles (ocular myopathy). Brain 24: 115

    Article  Google Scholar 

  • Klinkerfuss GH (1967) An electron microscopic study of myotonic dystrophy. Arch Neurol 16: 181

    Article  PubMed  CAS  Google Scholar 

  • Kocen RS, Thomas PK (1970) Peripheral nerve involvement in Fabry’s disease. Arch Neurol 22: 81

    Article  PubMed  CAS  Google Scholar 

  • Kocen RS, King RHM, Thomas PK, Haas LF (1973) Nerve biopsy findings in two cases of Tangier disease. Acta Neuropathol (Berl) 26: 317

    Article  CAS  Google Scholar 

  • Lake BD, Wilson J (1975) Zebra body myopathy: Clinical, histochemical and ultrastructural studies. J Neurol Sci 24: 437

    Article  PubMed  CAS  Google Scholar 

  • Landon DB, Hall SM (1976) The myelinated nerve fibre. In Landon DN (ed) The peripheral nerve. Chapman & Hall, London, p 1

    Google Scholar 

  • Lawrence DG, Locke S (1963) Neuropathy in children with diabetes mellitus. Br Med J 11: 784

    Article  Google Scholar 

  • Lindstrom JM, Lambert E (1978) Content of acetylcholine receptor and antibodies bound to receptor in myasthenia gravis, experimental autoimmune myasthenia gravis and Eaton-Lambert syndrome. Neurology (Minneap) 28: 130

    CAS  Google Scholar 

  • Lindstrom JM, Seybold ME, Lennon VA, Whittingham S, Duane DD (1976) Antibody to acetylcholine receptor in myasthenia gravis Prevalence, clinical correlates and diagnostic value. Neurology (Minneap) 26: 1054

    CAS  Google Scholar 

  • Lyon G (1969) Ultrastructure of a nerve biopsy from a case of early infantile chronic neuropathy. Acta Neuropathol (Berl) 13: 131

    Article  CAS  Google Scholar 

  • Mars H, Lewis LA, Robertson AL, Butkus A, Williams GH (1969) Familial hypo ß lipoproteinaemia. Am J Med 46: 886

    Article  PubMed  CAS  Google Scholar 

  • McArdle B (1951) Myopathy due to a defect in muscle glycogen breakdown. Clin Sci Mol Med 10: 13

    CAS  Google Scholar 

  • McComas AT (1977) Neuromuscular function and disorders. Butterworths, London

    Google Scholar 

  • McLellan DL, Swash M (1976) Longitudinal sliding of the median nerve during movement. J Neurol Neurosurg Psychiatry 38: 506

    Google Scholar 

  • Morgan-Hughes JA, Daviniza P, Kahn SN, Landon DN, Sherratt RM, Land SM, Clark JB (1978) A mitochondrial myopathy characterized by a deficiency in reducible cytochromes. Brain 100: 617

    Article  Google Scholar 

  • Moulds RFW, Denborough MA (1972) Procaine in malignant hyperpyrexia. Br Med J iv: 526

    Google Scholar 

  • Mellick RS, Mahler RF, Hughes BP (1962) McArdle’s syndrome Phospharylase deficient myopathy. Lancet 1: 1045

    Article  PubMed  CAS  Google Scholar 

  • Milhorat AT, Shafiq SA, Goldstone L (1966) Changes in muscle structure in dystrophic patients, carriers and siblings seen by electron microscopy Correlation with levels of serum creatine phospholeinase Ann NY Acad Sci 138: 246

    CAS  Google Scholar 

  • Mokri B, Engel AG (1975) Duchenne dystrophy—electron microscopic findings pointing to a basic or early abnormality in the plasma membrane of the muscle fibre. Neurology (Min-neap) 25: 1111

    CAS  Google Scholar 

  • Moosa A, Dubowitz V (1970) Peripheral neuropathy in Cockayne’s syndrome. Arch Dis Child 45: 674

    Article  PubMed  CAS  Google Scholar 

  • Namba T, Brunner NG, Brown SB, Mugurama M, Grob D (1971) Familial myasthenia gravis. Arch Neurol 25: 49

    Article  PubMed  CAS  Google Scholar 

  • Namba T, Brunner NG, Grob D (1978) Myasthenia gravis in patients with thymoma with particular reference to onset after thymectomy. Medicine (Baltimore) 57: 411

    CAS  Google Scholar 

  • Neville HE, Brooke MH (1971) Central core fibres: Structured and unstructured (Abstract). Excerpta Medica, Amsterdam, p 31 (ICS no. 237)

    Google Scholar 

  • Neville HE, Brooke MH (1973) Central core fibres: Structured and unstructured. In: Kakulas BA (ed) Basic research in myology, part I. Excerpta Medica, Amsterdam, p 497 (ICS no. 294 )

    Google Scholar 

  • Ochoa J (1976) The unmyelinated nerve fibre. In: Landon DN (ed) The peripheral nerve. Chapman & Hall, London, p. 106

    Google Scholar 

  • Ochoa J, Mair WG (1969) The normal sural nerve in man 1 Ultrastructure and numbers of fibres and cells. Acta Neuropathol (Berl) 13: 197

    Article  CAS  Google Scholar 

  • Ochoa J, Danta G, Fowler TJ, Gilliatt RW (1971) Nature of the nerve lesion caused by a pneumatic tourniquet. Nature, 233: 265

    Article  PubMed  CAS  Google Scholar 

  • Olsson Y, Säve-Soderbergh J, Sourander P, Angerwall L (1968) A patho-anatomical study of the central and peripheral nervous system in diabetics of early onset and long duration. Pathol Eur 3: 62

    PubMed  CAS  Google Scholar 

  • Ontell M (1974) Muscle satellite cells, A validated technique for light microscopic identification and a quantitative study of changes in their population following denervation. Anat Rec 178: 211

    Article  PubMed  CAS  Google Scholar 

  • Osserman KE (1958) Myasthenia gravis. Grune & Stratton, New York

    Google Scholar 

  • Pearce GW, Pearce JMS, Walton JN (1966) The Duchenne type muscular dystrophy, Histopathological studies of the carrier state. Brain 89: 109

    Google Scholar 

  • Pestronk D, Drachman DB (1978) A new method for demonstrating sprouting at neuromuscular terminals. Muscle Nerve 1: 40

    Article  Google Scholar 

  • Peter JB, Barnard VR, Edgerton VR, Gillespie CA, Stempel KE (1972) Metabolic profiles of three fibre types of skeletal muscles in guinea pigs and rabbits. Biochemistry 11: 2627

    Article  PubMed  CAS  Google Scholar 

  • Polgar J, Johnson MA, Weightman D, Appleton D (1972) Data on fibre size in thirty-six human muscles. J Neurol Sci 19: 307

    Article  Google Scholar 

  • Pirskanen R (1976) Genetic association between myasthenia gravis and the H-LA system. J Neurol Neurosurg Psychiatry 39: 23

    Article  PubMed  CAS  Google Scholar 

  • Prineas JW (1972) Acute idiopathic polyneuritis, An electron microscopic study. Invest 26: 133

    CAS  Google Scholar 

  • Refsum S (1946) Heredopathia atactica polyneuritiformis, A familial syndrome not hitherto described. Acta Psychiatr Scand [Suppl] 38 1: 303

    Google Scholar 

  • Reznik N (1973) Current concepts of skeletal muscle regeneration. In: Pearson CM (ed) The striated muscle. Williams & Wilkins, Baltimore, p 185

    Google Scholar 

  • Reznik M, Engel WK (1970) Ultrastructural and histochemical correlations of experimental muscle regeneration. J Neurol Sci 11: 167

    Article  PubMed  CAS  Google Scholar 

  • Ridley A (1969) The neuropathy of acute intermittent porphyria. Q J Med 38: 307

    PubMed  CAS  Google Scholar 

  • Ridley A (1975) Porphyric neuropathy. In: Dyck PJ, Lambert EG, Thomas PK (eds) Peripheral neuropathy, vol 2. Saunders, London Philadelphia, p 942

    Google Scholar 

  • Ringel SP, Bender AN, Engel WK (1976) Extrajunctional acetylcholine receptors, Alterations in human and experimental neuromuscular diseases. Arch Neurol 33: 751

    Google Scholar 

  • Rosman NP, Kakulas BA (1966) Mental deficiency associated with muscular dystrophy, A neuropathological study. Brain 89: 769

    Google Scholar 

  • Russell DS (1953) Histological changes in the striped muscles in myasthenia gravis. J Pathol Bacteriol 65: 279

    Article  PubMed  CAS  Google Scholar 

  • Sabin TD, Swift TR (1975) Leprosy In: Dyck PJ, Thomas PK, Lambert EH (eds) Peripheral neuropathy, vol 2. Saunders, London Philadelphia, p 1166

    Google Scholar 

  • Santa T, Engel AG, Lambert EH (1972) Histometric study of neuromuscular junction 1 myasthenia gravis. Neurology (Minneap) 22: 71

    CAS  Google Scholar 

  • Sato T, Walker DL, Peters HA, Reese HH, Chou SM (1971) Chronic polymyositis and myxovirus-like inclusions: Electron microscopic and viral studies. Arch Neurol 24: 409

    Google Scholar 

  • Schaumberg HH, Spencer PS (1979) Toxic neuropathies. Neurology (Minneap) 29: 429

    Google Scholar 

  • Schmalbruch H (1976) Muscle fibre splitting and regeneration in diseased human muscle. Neuropathol Appl Neurobiol 2: 3

    Article  Google Scholar 

  • Schmid R, Mahler R (1959) Chronic progressive myopathy with myoglobinuria: demonstration of a glycogenolytic defect in the muscle. J Clin Invest 38: 2044

    Article  PubMed  CAS  Google Scholar 

  • Schotland DL (1977) Duchenne dystrophy—a freeze fracture study. In: Rowland LP (ed) Pathogenesis of human muscular dystrophies. Excerpta Medica, Amsterdam, p 562 (ICS no 404 )

    Google Scholar 

  • Schwartz MS, Swash M (1975) Scapulo-peroneal atrophy with sensory involvement Davidenkow’s syndrome. J Neurol Neurosurg Psychiatry 38: 1063

    Article  PubMed  CAS  Google Scholar 

  • Schwartz MS, Sargeant M, Swash M (1976) Longitudinal fibre splitting in neurogenic muscular disorders: Its relation to the pathogenesis of `myopathic’ change. Brain 99: 617

    Google Scholar 

  • Schwartz MS, Moosa A, Dubowitz V (1977a) Correlation of single fibre EMG and muscle histochemistry using an open biopsy recording technique. J Neurol Sci 31: 309

    Article  Google Scholar 

  • Schwartz MS, Sargeant MK, Swash M (1977b) Neostigmineinduced end-plate proliferation in the rat. Neurology (Min-neap) 27: 289

    CAS  Google Scholar 

  • Schwartz MS, Swash M, Gross M (1978) Benign post-infection polymyositis. Br Med J 11: 1256

    Article  Google Scholar 

  • Seitelberger F, Wanko T, Gavin MA (1961) The muscle fibre in central core disease, histochemical and electron microscopic observations. Acta Neuropathol (Berl) 1: 223

    Article  Google Scholar 

  • Shafiq SA, Dubowitz V, Peterson HdeC, Milhorat AT (1967) Nemaline myopathy, Report of a fatal case, with histochemical and electron microscopic studies. Brain 90: 817

    Google Scholar 

  • Sher JH, Rimalovski AB, Athanassiades TJ, Aronson SM (1967) Familial centronuclear myopathy, A clinical and pathological study. Neurology (Minneap) 17: 727

    Google Scholar 

  • Sheramata W, Kott S, Cyr DP (1971) The Chediak-Higashi—Steinbrinck syndrome. Arch Neurol 25: 289

    Article  PubMed  CAS  Google Scholar 

  • Shy GM, Magee KR (1956) A new congenital non-progressive myopathy. Brain 79: 610

    Article  PubMed  CAS  Google Scholar 

  • Shy GM, Engel WK, Somers JE, Wanko T (1963) Nemaline myopathy: A new congenital myopathy. Brain 86: 793

    Google Scholar 

  • Sloper JC, Pegrum GD (1967) Regeneration of crushed mammalian skeletal muscle and effects of steroids. J Pathol 93: 47

    Article  CAS  Google Scholar 

  • Sourander P, Olsson Y (1968) Peripheral neuropathy in globoid cell leucodystrophy ( Morbus Krabbe ). Acta Neuropathol (Berl) 11: 69

    Google Scholar 

  • Spiro AJ, Shy GM, Gonatas NK (1966) Myotubular myopathy. Arch Neurol 14: 1

    Article  PubMed  CAS  Google Scholar 

  • Stern GM, Hall JM, Robinson DC (1964) Neonatal myasthenia gravis. Br Med J 2: 284

    Article  PubMed  CAS  Google Scholar 

  • Steinberg D, Mize C, Avigan J, Falls HM, Eldjarn L, Try K, Stokke O, Refsum S (1966) On the metabolic error in Refsum’s disease. Trans Am Neurol Assoc 91: 168

    Google Scholar 

  • Stevens JC, Lofgren EP, Dyck PJ (1975) Biopsy of peripheral nerves. In: Dyck PJ, Thomas PK, Lambert EH (eds) Peripheral neuropathy. Saunders, London Philadelphia, p 410

    Google Scholar 

  • Sunderland S (1978) Nerves and nerve injuries. Churchill Livingstone, Edinburgh

    Google Scholar 

  • Swash M (1979) Guillain-Barré syndrome, Clinical aspects. J R Soc Med 12: 670

    Google Scholar 

  • Swash M, Fox KP (1972) Muscle spindle innervation in man. J Anat 112: 61

    PubMed  CAS  Google Scholar 

  • Swash M, Fox KP (1974) The pathology of the muscle spindle, Effect of denervation. J Neurol Sci 22: 1

    Google Scholar 

  • Swash M, Fox KP (1975a) Abnormal intrafusal muscle fibres in myotonic dystrophy, A study using serial sections. J Neurol Neurosurg Psychiatry 38: 91

    Google Scholar 

  • Swash M, Fox KP (1975b) The fine structure of the spindle abnormality in myotonic dystrophy. Neuropathol Appl Neurobiol 1: 171

    Article  Google Scholar 

  • Swash M, Fox KP (1976) The pathology of the muscle spindle in Duchenne muscular dystrophy. J Neurol Sci 29: 17

    Article  PubMed  CAS  Google Scholar 

  • Swash M, Schwartz MS (1977) Implications of longitudinal fibre splitting in myopathic and neurogenic disorders. J Neurol Neurosurg Psychiatry 40: 1152

    Article  PubMed  CAS  Google Scholar 

  • Swash M, van den Noort S, Craig JW (1970) Myopathy associated with diabetes mellitus in two sisters. Neurology (Minneap) 20: 694

    CAS  Google Scholar 

  • Swash M, Sargeant MK, Schwartz MS (1978a) Pathogenesis of longitudinal splitting of muscle fibres in neurogenic disorders and polymyositis. Neuropathol Appl Neurobiol 4: 99

    Article  PubMed  CAS  Google Scholar 

  • Swash M, Schwartz MS, Sargeant MK (1978b) The significance of ragged-red fibres in neuromuscular disease. J Neurol Sci 36: 347

    Article  Google Scholar 

  • Sweeney VP, Pathak MA, Asbury AK (1970) Acute intermittent porphyria: Increased ALA synthetase activity during an acute attack. Brain 83: 369

    Article  Google Scholar 

  • Tallis R, Staniforth P, Fisher TR (1978) Neurophysiological studies of autogenous sural nerve grafts. J Neurol Neurosurg Psychiatry 41: 677

    Article  PubMed  CAS  Google Scholar 

  • Tarui S, Oluno G, Ikura Y, Tanaka T, Suda M, Nishikawa M (1965) Phosphofructokinase deficiency in skeletal muscle, a new type of glycogenosis. Biochem Biophys Res Commun 19: 517

    Article  PubMed  CAS  Google Scholar 

  • Thomas KP, Calne DB, Elliott CF (1972) X-linked scapulo- peroneal syndrome. J Neurol Neurosurg Psychiatry 35: 208

    Article  PubMed  CAS  Google Scholar 

  • Thomas PK, Lascelles RG (1966) The pathology of diabetic neuropathy. Q J Med 35: 489

    Google Scholar 

  • Thomas PK, Lascelles RG, Hallpike JF, Hewer RC (1969) Recurrent and chronic relapsing Guillain—Barré polyneuritis. Brain 92: 589

    Article  PubMed  CAS  Google Scholar 

  • Van Wijngaarden GK, Bethlem J (1971) The facioscapulohumeral syndrome. In: Kakulas BA (ed) Second International Congress on Muscle Diseases. Excerpta Medica, Amsterdam, p 54 (ICS no. 237 )

    Google Scholar 

  • Victor M, Hayes R, Adams RD (1962) Oculopharyngeal muscular dystropy. A familial disease of late life characterized by dysphagia and progressive ptosis of the eyelids N Engl J Med 267: 1267

    CAS  Google Scholar 

  • Vincent A, Scadding GK, Thomas HC, Newsom Davis J (1978) In-vitro synthesis of anti-acetylcholine receptor antibody to thymic lymphocytes in myasthenia gravis. Lancet 1: 305

    Article  PubMed  CAS  Google Scholar 

  • Walton JN, Adams RD (1958) Polymyositis Williams & Wilkins, Baltimore

    Google Scholar 

  • Webb JN (1977) Cell death in developing skeletal muscle, Histiochemistry and ultrastructure. J Pathol 123: 175

    Article  PubMed  CAS  Google Scholar 

  • Weller RO, McArdle B (1971) Calcification within muscle fibres in the periodic paralyses. Brain 94: 263

    Article  PubMed  CAS  Google Scholar 

  • Whitaker JN, Engel WK (1972) Vascular deposits of immunoglobulins and complement in idiopathic inflammatory myopathy. N Engl J Med 286: 333

    Article  PubMed  CAS  Google Scholar 

  • Whitaker JN, Engel WK (1973) Mechanisms of muscle injury in idiopathic inflammatory myopathy. N Engl J Med 288: 434 and 289: 107

    CAS  Google Scholar 

  • Whiteley AM, Schwartz MS, Sachs JA, Swash M (1976) Congenital myasthenia gravis, Clinical and HLa studies in two brothers. J Neurol Neurosurg Psychiatry 39: 1145

    Google Scholar 

  • Wochner RD, Dres G, Strober W, Waldmann TA (1966) Accelerated breakdown of IgG in myotonic dystrophy, A hereditary error of immunoglobulin catabolism. J Clin Invest 45: 321

    Google Scholar 

  • Young JZ (1942) Functional repair of nervous tissue. Physiol Rev 22: 318

    Google Scholar 

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Swash, M. (1981). Muscle and Peripheral Nerve. In: Berry, C.L. (eds) Paediatric Pathology. Springer, London. https://doi.org/10.1007/978-1-4471-3304-9_11

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