Skip to main content
SpringerLink
Log in

Macroscopy, Microscopy, and Sampling

  • Chapter
Introduction to Biopsy Interpretation and Surgical Pathology

  • 66 Accesses

Abstract

The gross examination and sampling of surgical resections and biopsy specimens for histology is an important responsibility of the histopathologist, a detailed practical guide to which can be found elsewhere (Kennedy, 1977). Blocks of tissue for histology should always be taken with due regard to the particular problem under investigation, conscious of the local anatomy, and with the aim of minimising sampling error.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 74.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Abrahams C (1978) The “scrimp” technique—A method for the rapid diagnosis of surgical pathology specimens. Histopathology 2:255–266

    Article  PubMed  CAS  Google Scholar 

  • Baron E (1939) Aspiration for the removal of biopsy material from the liver. Arch Intern Med 63:276–289

    Article  Google Scholar 

  • Baunsgaard P, Sanchez GC, Lundborg CJ (1979) The variation of pathological changes in the liver evaluated by double biopsies. Acta Pathol Microbiol Scand [A] 87:51–57

    CAS  Google Scholar 

  • Berg JW, Robbins GF (1962) A late look at the safety of aspiration biopsy. Cancer 15:826–827

    Article  PubMed  CAS  Google Scholar 

  • Berlin RB, Brines OA (1951) Detection of lymph node involvement in cancer. Am J Clin Pathol 21:332–337

    PubMed  CAS  Google Scholar 

  • Davies JD, Roberts G, Richardson PJ (1973) A serial whole-organ slicing technique for examining surgically resected breasts. J Clin Pathol 26:891–892

    Article  PubMed  CAS  Google Scholar 

  • Dekker A, Bupp PA (1978) Cytology of serous effusions. An investigation into the usefulness of cell blocks versus smears. Am J Clin Pathol 70:855–860

    PubMed  CAS  Google Scholar 

  • Dudgeon LS, Patrick C (1927) A method for the rapid microscopical diagnosis of tumours. Br J Surg 15:250–260

    Article  Google Scholar 

  • Farrer-Brown G, Bennett MH, Harrison CV, Millett Y, Jelliffe AM (1972) The diagnosis of Hodgkin’s disease in surgically excised spleens. J Clin Pathol 25:294–300

    Article  PubMed  CAS  Google Scholar 

  • Fox CH (1979) Innovation in medical diagnosis: The Scandinavian curiosity. Lancet 1:1387–1388

    Article  PubMed  CAS  Google Scholar 

  • Frable WJ (1976) Thin-needle aspiration biopsy: A personal experience with 469 cases. Am J Clin Pathol 65:168–182

    PubMed  CAS  Google Scholar 

  • Franks LM (1954) Latent carcinoma of the prostate. J Pathol Bacteriol 68:603–616

    Article  PubMed  CAS  Google Scholar 

  • Gallagher HS, Martin JE (1969) The study of mammary carcinoma by mammography and whole organ sectioning. Cancer 23:855–873

    Article  Google Scholar 

  • Gladstone SA (1948) Sponge biopsy in cancer diagnosis. Am J Med 5:849–852

    Article  PubMed  CAS  Google Scholar 

  • Hajdu SI, Melamed MR (1973) The diagnostic value of aspiration smears. Am J Clin Pathol 59:350–356

    PubMed  CAS  Google Scholar 

  • Hatfield ARW, Slavin G, Segal AW, Levi AJ (1975) Importance of the site of endoscopic gastric biopsy in ulcerating lesions of the stomach. Gut 16:884–886

    Article  PubMed  CAS  Google Scholar 

  • Hawk WA, Crile G, Hazard JB, Barrett DL (1966) Needle biopsy of the thyroid gland. Surg Gynecol Obstet 122:1053–1065

    PubMed  CAS  Google Scholar 

  • Kawai K, Takemoto T, Suzuki S, Ida K (1979) Proposed nomenclature and classification of the dye-spraying techniques in endoscopy. Endoscopy 1:23–25

    Article  Google Scholar 

  • Kellow WF, Cotsonas NJ, Chomet B, Zimmerman HJ (1959) Evaluation of the adequacy of needle biopsy specimens of the kidney: An autopsy study. Arch Intern Med 104:353–359

    Article  PubMed  CAS  Google Scholar 

  • Kennedy A (1977) Basic techniques in diagnostic histopathology. Churchill Livingstone, London Edinburgh

    Google Scholar 

  • Martin HE, Ellis EB (1930) Biopsy by needle puncture and aspiration. Ann Surg 92:169–181

    Article  PubMed  CAS  Google Scholar 

  • Meatheringham RE, Ackerman LV (1947) Aspiration biopsy of lymph nodes: A critical review of results of 300 aspirations. Surg Gynecol Obstet 84:1071–1076

    PubMed  CAS  Google Scholar 

  • Meyer JS (1973) Rapid cytologic identification of renal cortex in kidney biopsies. Am J Clin Pathol 59:595–600

    PubMed  CAS  Google Scholar 

  • Monroe CW (1948) Lymphatic spread of carcinoma of the breast. Arch Surg 57:479–486

    Article  PubMed  CAS  Google Scholar 

  • Moore RD, Reagan JW (1953) Cellular study of lymph node imprints. Cancer 6:606–618

    Article  PubMed  CAS  Google Scholar 

  • Nichols TM, Boyes DA, Fidler HK (1968) Advantages of routine step serial sectioning of cervical cone biopsies. Am J Clin Pathol 49:342–346

    PubMed  CAS  Google Scholar 

  • Paul J (1970) Cell and tissue culture, 4th edn. Livingstone, Edinburgh London

    Google Scholar 

  • Pease DC (1964) Histological techniques for electron microscopy. Academic Press, New York London, p 13

    Google Scholar 

  • Pickren JW (1961) Significance of occult metastases: A study of breast cancer. Cancer 14:1266–1271

    Article  PubMed  CAS  Google Scholar 

  • Rosenberg E, Black H (1959) The value of biopsy of cores of fresh hepatic tissue in the diagnosis of schistosomiasis. Am J Clin Pathol 32:472–473

    PubMed  CAS  Google Scholar 

  • Rubio CA, Thomassen P, Sodeberg G, Kock Y (1978) Big cones and little cones. Histopathology 2:133–143

    Article  PubMed  CAS  Google Scholar 

  • Saltzstein SL (1960) Histologic diagnosis of breast carcinoma with the Silverman needle biopsy. Surgery 48:366–374

    PubMed  CAS  Google Scholar 

  • Saphir O, Amromin GD (1948) Obscure axillary lymph-node metastasis in carcinoma of the breast. Cancer 1:238–241

    Article  PubMed  CAS  Google Scholar 

  • Silverberg SG, Vidone RA (1966) Carcinoma of the thyroid in surgical and post-mortem material. Analysis of 300 cases at autopsy and literature review. Ann Surg 164:291–299

    Article  PubMed  CAS  Google Scholar 

  • Soloway RD, Bagenstoss AH, Schoenfield LJ, Summerskill WHJ (1971) Observer error and sampling variability tested in evaluation of hepatitis and cirrhosis by liver biopsy. Am J Dig Dis 16:1082–1086

    Article  PubMed  CAS  Google Scholar 

  • Te Velde J, Burkhardt R, Kleiverda K, Leenheers-Binnendijk L, Sommerfeld W (1977) Methyl- methacrylate as an embedding medium in histopathology. Histopathology 1:319–330

    Article  Google Scholar 

  • Wagoner G, Ulevitch H, Gall EA, Schiff L (1951) Biopsy of needle specimens of liver tissue. VI. Comparison of findings on biopsy and at autopsy. Am J Clin Pathol 21:338–341

    PubMed  CAS  Google Scholar 

  • Wilkinson EJ, Hause L (1974) Probability in lymph node sectioning. Cancer 33:1269–1274

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. University of Sheffield Medical School, Sheffield, S10 2RX, England

    J. C. E. Underwood MD, MRCPath. (Senior Lecturer in Pathology, Honorary Consultant Histopathologist)

  2. Royal Hallamshire Hospital, Sheffield, S10 2RX, England

    J. C. E. Underwood MD, MRCPath. (Senior Lecturer in Pathology, Honorary Consultant Histopathologist)

Authors
  1. J. C. E. Underwood MD, MRCPath.
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

Copyright information

© 1981 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Underwood, J.C.E. (1981). Macroscopy, Microscopy, and Sampling. In: Introduction to Biopsy Interpretation and Surgical Pathology. Springer, London. https://doi.org/10.1007/978-1-4471-3301-8_2

Download citation

  • DOI: https://doi.org/10.1007/978-1-4471-3301-8_2

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-3303-2

  • Online ISBN: 978-1-4471-3301-8

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation