Abstract
Any disease process that has a multitude of therapeutic approaches is generally a condition without a truly effective treatment (Hanno and Wein 1987). Interstitial cystitis is such an entity and remains enigmatic and problematic with respect to its etiology, pathology, diagnosis and treatment. The only certainty is that it is an important lesion causing transmural inflammation of the bladder wall which confers on its victim marked irritative voiding symptoms and consequentially intense misery and suffering. According to Messing (Messing and Stamey 1978), the hallmark of interstitial cystitis is glomerulation upon the second bladder distension and the characteristic histological finding is submucosal edema and vasodilation. An infiltrate of mast cells is characteristically found in the bladder wall.
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Siegel, A., Snyder, J., Raz, S. (1990). Surgical Therapy of Interstitial Cystitis. In: Hanno, P.M., Staskin, D.R., Krane, R.J., Wein, A.J. (eds) Interstitial Cystitis. Springer, London. https://doi.org/10.1007/978-1-4471-3293-6_25
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DOI: https://doi.org/10.1007/978-1-4471-3293-6_25
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