Abstract
Association with HLA, in particular class II genes (DQB1, DRB1), has been suggested as one of the genetic factors involved in TGCT development [1]. The present study used a marker haplotyping method in trios (parents or spouse and child) to replicate the previous findings, obtained through HLA typing.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Ozdemir E, Kakehi Y, Mishina M et al. High-resolution HLA-DRB1 and DQB1 genotyping in Japanese patients with testicular germ cell carcinoma. Br J Cancer 1997;76:1348–1352
Sonneveld DJA, Schaapveld M, Sleijfer DTh, et al. Geographic clustering of testicular cancer incidence in the northern part of the Netherlands. Br J Cancer 1999;81:1262–1267
Beckmann L, Fischer C, Deck K-G, Nolte IM, Meerman GJ, Chang-Claude J. Exploring haplotype sharing methods in general and isolated populations to detect gene(s) of a complex genetic trait. Genetic Epidemiol 2001;in press
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2002 Springer-Verlag London Limited
About this paper
Cite this paper
Lutke Holzik, M.F. et al. (2002). No Association Between HLA Class II Genes and Testicular Germ Tumour (TGCT) with Genotyping of the HLA-Region on Chromosome 6p21 and Haplotype Sharing Analysis. In: Harnden, P., Joffe, J.K., Jones, W.G. (eds) Germ Cell Tumours V. Springer, London. https://doi.org/10.1007/978-1-4471-3281-3_8
Download citation
DOI: https://doi.org/10.1007/978-1-4471-3281-3_8
Publisher Name: Springer, London
Print ISBN: 978-1-4471-3283-7
Online ISBN: 978-1-4471-3281-3
eBook Packages: Springer Book Archive