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Treatment of Primary Intracranial Germ Cell Tumours with Carboplatin-based Chemotherapy and Focal Irradiation

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Abstract

In the SFOP TC-90 and TC-92 protocols, patients with intracranial germinomas and secreting germ cell tumours (sGCT) were treated with a combination of chemotherapy and focal radiotherapy. One chemotherapy cycle included alternating Carboplatin-VP16 and Ifosfamide-VP16. Germinoma patients received two cycles followed by 40 Gy focal radiotherapy, and sGCT three or four cycles followed by focal 55 Gy. Metastatic patients received craniospinal radiotherapy.

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© 2002 Springer-Verlag London Limited

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Patte, C. et al. (2002). Treatment of Primary Intracranial Germ Cell Tumours with Carboplatin-based Chemotherapy and Focal Irradiation. In: Harnden, P., Joffe, J.K., Jones, W.G. (eds) Germ Cell Tumours V. Springer, London. https://doi.org/10.1007/978-1-4471-3281-3_29

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  • DOI: https://doi.org/10.1007/978-1-4471-3281-3_29

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-3283-7

  • Online ISBN: 978-1-4471-3281-3

  • eBook Packages: Springer Book Archive

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