Abstract
Neurophysiological studies usually show some abnormality of nerve conduction in GBS and may eventually show evidence of denervation in severe cases. They are an important adjunct in the diagnosis but even extensive studies may be normal at first in occasional clinically typical cases. Neurophysiological techniques have been particularly valuable in probing the underlying pathophysiology of GBS. Biopsies give information about only a tiny sample of a particular cutaneous sensory nerve which is usually relatively unaffected, while autopsy studies have their own limitations. Albers (1987) has provided an excellent review to which must be added interesting recent studies concerning the pattern of conduction failure (Van der Meche et al. 1988) and the relationship between small distally evoked action potentials and poor prognosis (Cornblath et al. 1988; Winer et al. 1988).
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Hughes, R.A.C. (1990). Clinical Neurophysiology. In: Guillain-Barré Syndrome. Clinical Medicine and the Nervous System. Springer, London. https://doi.org/10.1007/978-1-4471-3175-5_7
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DOI: https://doi.org/10.1007/978-1-4471-3175-5_7
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