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Plasma Exchange

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Clinical Aspects of Blood Viscosity and Cell Deformability

Abstract

Plasma exchange has been used as a therapeutic tool since the beginning of the century (Abel et al., 1914). However its use has increased markedly since the development of efficient machines to perform the manoeuvre. A distinction is sometimes drawn between the terms plasmapheresis and plasma exchange. Plasmapheresis (plasma + Gr. aphairesis or removal) strictly means the removal of plasma (Buskard, 1978). Plasma exchange implies the removal of plasma and replacement with whole or fractionated plasma or plasma substitutes. Large-volume plasmapheresis is not possible without replacement, so plasma exchange is the more appropriate term.

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References

  • Abel J J, Rowntree L G, Turner B B (1914) Plasma removal with return of the corpuscles. J Pharmacol Exp Ther 5: 625–641

    CAS  Google Scholar 

  • Bayer W L, Farrales F B, Summers T, Belcher C (1975) Coagulation studies after Plama Exchange with plasma protein fraction and lactated Ringer’s solution. In: Goldman J M, Lowenthal R M (eds). Leucocytes: Separation, collection and transfusion. Academic Press, London

    Google Scholar 

  • Blättler W, Straub P W, Jeanneret C, Horaic G S (1979) Effect of low fibrinogen concentrations on the rheology of human blood in vitro. Am J Physiol 236: H447 - H450

    PubMed  Google Scholar 

  • Braasch D (1974) Annotation: Red cell elasticity. Br J Haematol 24: 405–407

    Article  Google Scholar 

  • Buskard N A (1978) Plasma exchange and plasmapheresis (editorial). Can Med Assoc J 119: 681–683

    PubMed  CAS  Google Scholar 

  • Charm S E, McComis W, Kurland G (1964) Rheology and structure of blood suspensions. J Appl Physiol 19: 127–133

    PubMed  CAS  Google Scholar 

  • Chien S (1970) Shear dependence of effective cell volume as a determinant of blood viscosity. Science 168: 977–978

    Article  PubMed  CAS  Google Scholar 

  • Chien S, Usami S, Dellenback R J, Gregersen M I (1970) Shear dependent deformation of erythrocytes in rheology of human blood. Am J Physiol 219: 136–142

    PubMed  CAS  Google Scholar 

  • Coffman J D, Cohen A S (1971) Total and capillary blood flow in Raynaud’s Phenomenon. N Engl J Med 285: 259–263

    Article  PubMed  CAS  Google Scholar 

  • Cohn E J, Tullis J L, Surgentor D M, Batchelor W H, D’Hont M D (1951) Biochemistry and bio-mechanics of blood collection, processing and analysing of human blood and other tissues. Address presented before the National Academy of Science, Yale University, New Haven

    Google Scholar 

  • Culliver H, Pennington D G (1979) Mechanisms of vascometer reactions in the use of SPPS. Vox Sang 36: 201–207

    Article  PubMed  CAS  Google Scholar 

  • Dintenfass L (1977) Haemorheological factors in Raynaud’s Syndrome. Angiology 28: 472–481

    Article  PubMed  CAS  Google Scholar 

  • Dodds A J, O’Reilly M J G, Yates C J P, Cotton L T, Flute P T, Dormandy J A (1979) Haemorheological response to Plasma Exchange in Raynaud’s Syndrome. Br Med J 4: 1186–1187

    Article  Google Scholar 

  • Dormandy J A (1971) Influence of blood viscosity on blood flow and the effect of low molecular weight Dextran. Br Med J 4: 716–719

    Article  PubMed  CAS  Google Scholar 

  • Dormandy J A (1974) Mechanical and engineering problems of blood viscosity. Biomed Eng 9: 284–303

    PubMed  CAS  Google Scholar 

  • Drummond M M, Lowe G D O, Belch J J F, Forbes C D, Barbenel J C (1979) An assessment of red cell deformability using a simple filtration method. Thromb Haemostas 42: 106

    Google Scholar 

  • Friedman B A, Schork M A, Mocniak J L, Oberman H A (1975) Short-term and long-term effects of plasmapheresis on serum proteins and immunoglobulins. Transfusion 15: 467–472

    Article  PubMed  CAS  Google Scholar 

  • Goyle K B, Dormandy J A (1974) Abnormal blood viscosity in Raynaud’s Phenomenon. Lancet i: 1317–1318

    Google Scholar 

  • Isbister J P, Biggs J L (1976) Reactions to rapid infusion of stable plasma protein solution during large volume plasma exchange. Anaesth Intensive Care 4: 105–107

    PubMed  CAS  Google Scholar 

  • Izaka K, Tsutsui E, Mima Y, Hasegawa E (1974) A bradykinin-like substance in heat-treated human plasma protein solution. Transfusion 4: 242–248

    Article  Google Scholar 

  • Judson G, Jones A, Kellogg R, Buckner D, Eisel R, Perry S, Greenough W (1968) Closed continuous flow centrifuge. Nature (London) 217: 816–818

    Article  CAS  Google Scholar 

  • Keller A J, Urbaniak S J (1978) Intensive plasma exchange on the Cell Separator: Effects on serum immunoglobulins and complement components. Br J Haematol 38: 531–540

    Article  PubMed  CAS  Google Scholar 

  • Keller A J, Chirnside A, Urbaniak S J (1979) Coagulation abnormalities produced by plasma exchange on the cell separator with special reference to fibrinogen and platelet levels. Br J Haematol 42: 593–603

    Article  PubMed  CAS  Google Scholar 

  • Kilpatrick D, Fleming J, Clyne C, Thompson G R (1979) Reduction of blood viscosity following plasma exchange. Atherosclerosis 32: 301–306

    Article  PubMed  CAS  Google Scholar 

  • Kincaid-Smith P, d’Apice A J F (1978) Plasmapheresis in rapidly progressive glomerulonephritis. Am J Med 65: 564–566

    Article  Google Scholar 

  • Leading Article (1978) Red cell deformability Lancet ii: 1348–1349

    Google Scholar 

  • McGrath M A, Penny R (1976) Paraproteinaemia: blood hyperviscosity and clinical manifestations. J Clin Invest 58: 1155–1162

    Article  PubMed  CAS  Google Scholar 

  • McGrath M A, Peek R, Penny R (1977) Blood hyperviscosity with reduced skin blood flow in scleroderma. Ann Rheum Dis 36: 569–574

    Article  PubMed  CAS  Google Scholar 

  • McGrath M A, Penny R (1978) Blood hyperviscosity in cryoglobulinaemia: temperature sensitivity and correlation with reduced skin blood flow. Aust J Exp Biol Med Sci 56: 127–137

    Article  PubMed  CAS  Google Scholar 

  • O’Reilly M J G, Talpos G, Roberts V C, White J M, Cotton L T (1979) Controlled trial of plasma exchange in the treatment of Raynaud’s Syndrome. Br Med J 1: 1113–1115

    Article  PubMed  Google Scholar 

  • Pinchling A J (1978) Plasma exchange. Br J Hosp Med 20: 552–559

    Google Scholar 

  • Powles R, Smith C, Kohn J, Hamilton Fairley G (1971) Method of removing abnormal protein rapidly from patients with malignant paraproteinaemias. Br Med J 3: 664–667

    Article  PubMed  CAS  Google Scholar 

  • Rampling M, Sirs J A (1972) The interactions of fibrinogen and dextrans with erythrocytes. J Physiol (London) 223: 199–212

    CAS  Google Scholar 

  • Russell J A, Toy J L, Powles R L (1977) Plasma exchange in malignant paraproteinaemias. Exp Haematol 5: 100–116

    Google Scholar 

  • Schmid-Schönbein H, Klose H J, Volger E (1972) Effect of colloidal plasma substitutes on microrheology of human blood. In: Messmer K, Schmid-Schönbein H (eds). Haemodilution: Theoretical basis and clinical application. Karger, Basel, New York, pp. 66–83

    Google Scholar 

  • Solomon A, Fahey J L (1963) Plasmapheresis therapy in macroglobulinaemia. Ann Intern Med 58: 789–800

    PubMed  CAS  Google Scholar 

  • Whitworth J A, d’Apice A J F, Kincaid-Smith P, Shulkes A A, Skinner S L (1978) Antihypertensive effect of plasma exchange. Lancet i: 1205

    Article  Google Scholar 

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Authors
  1. A. J. Dodds
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Editor information

Editors and Affiliations

  1. University Department of Medicine, Royal Infirmary, 86 Castle Street, G4 0SF, Glasgow, Scotland

    G. D. O. Lowe MB, ChB, MRCP (Lecturer in Medicine and Honorary Senior Registrar) & C. D. Forbes MD, FRCP (Senior Lecturer in Medicine and Honorary Consultant Physician) (Lecturer in Medicine and Honorary Senior Registrar) &  (Senior Lecturer in Medicine and Honorary Consultant Physician)

  2. Bioengineering Unit, University of Strathclyde, G4 0NW, Glasgow, Scotland

    J. C. Barbenel BDS, BSc, MSc, PhD, LDS, RCS, MInstP (Senior Lecturer) (Senior Lecturer)

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© 1981 Spring-Verlag Berling Heidelberg

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Dodds, A.J. (1981). Plasma Exchange. In: Lowe, G.D.O., Barbenel, J.C., Forbes, C.D. (eds) Clinical Aspects of Blood Viscosity and Cell Deformability. Springer, London. https://doi.org/10.1007/978-1-4471-3105-2_19

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  • DOI: https://doi.org/10.1007/978-1-4471-3105-2_19

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-3107-6

  • Online ISBN: 978-1-4471-3105-2

  • eBook Packages: Springer Book Archive

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