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Soft-Tissue Sarcoma

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Neonatal Tumours

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Abstract

Soft-tissue sarcomas are malignant mesenchymal or soft-tissue tumours that not only behave aggressively with infiltrative growth at the site of the tumour — as most soft-tissue tumours do — but also metastasize and show a definite malignant histological pattern, which is often difficult to determine with certainty. Soft-tissue sarcomas are thought to originate from undifferentiated mesenchymal cells, being the initial cells for the development of connective tissue, muscle, fat, tendon and nerve tissue, as well as vascular and lymphatic structures. The undifferentiated initial mesenchymal cells can either develop into differentiated cells of the above-mentioned soft tissues, becoming malignant secondarily, or become malignant in the undifferentiated state or in a state that does not allow recognition of the cell line they belong to. These tumours are classified as undifferentiated sarcoma. A simplified adaptation to the neonatal age group of the classification of benign and malignant soft-tissue tumours by Stout and Lattes1 and Krementz and Munchmore2 is shown in Table 7.1.

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Authors
  1. Peter Frey
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Editors and Affiliations

  1. Our Lady’s Hospital for Sick Children, National Children’s Hospital The Children’s Hospital, Dublin, Ireland

    Prem Puri MS, FACS (Consultant Paediatric Surgeon, Director of Research) (Consultant Paediatric Surgeon, Director of Research)

  2. Children’s Research Centre, Our Lady’s Hospital for Sick Children, Dublin, Ireland

    Prem Puri MS, FACS (Consultant Paediatric Surgeon, Director of Research) (Consultant Paediatric Surgeon, Director of Research)

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© 1996 Springer-Verlag London Limited

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Frey, P. (1996). Soft-Tissue Sarcoma. In: Puri, P. (eds) Neonatal Tumours. Springer, London. https://doi.org/10.1007/978-1-4471-3028-4_7

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  • DOI: https://doi.org/10.1007/978-1-4471-3028-4_7

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-3030-7

  • Online ISBN: 978-1-4471-3028-4

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