Abstract
Neonatal primary hepatic tumours are rare, and few cases are reported in both small and large series1–4. Benign tumours, including haemangioendothelioma and mesenchymal hamartoma, account for the majority of hepatic lesions; hepatic malignancies are extremely rare5–7. This low incidence of malignancy in the neonatal period is different from that of infancy and childhood in which two-thirds of patients present with hepatoblastoma and hepatocarcinoma1. Liver tumours of the newborn pose a challenge to all disciplines of paediatric practice. The benign vascular lesions can reach a large size before discovery, and may present with a life-threatening complication such as congestive heart failure, whereas the malignant tumours are unresectable in half the patients at the time of diagnosis8,9. A combined management plan by surgeons, neonatologists, oncologists and anaesthetists have minimized morbidity and mortality rates in both patient groups, although the prognosis for patients with malignant disease is still poor1,9.
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Sweed, Y., Bar-Maor, J.A. (1996). Liver Tumours. In: Puri, P. (eds) Neonatal Tumours. Springer, London. https://doi.org/10.1007/978-1-4471-3028-4_6
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