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Serous Neoplasms of the Ovary

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Pathology of the Ovary, Fallopian Tube and Peritoneum

Part of the book series: Essentials of Diagnostic Gynecological Pathology ((EDGP))

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Abstract

Our understanding of the biology and clinical behavior of serous neoplasms of the ovary has changed enormously over the past decade. It is now clear that although all serous tumors share a cell type reflecting tubal epithelium in various levels of differentiation, they appear to have different origins and distinct behaviors. Benign and borderline serous neoplasms, the most common variety, arise through a progressive accumulation of molecular defects and appear to arise in the ovary, possibly from endometriosis. High-grade serous carcinomas, in contrast, seem to arise, at least in part, on the epithelium of the distal fallopian tube.

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Authors and Affiliations

  1. Department of Pathology and Cytology, Södersjukhuset, Karolinska University Hospital, Stockholm, 11883, Sweden

    Eugenia C. Colón MD, PhD

  2. Department of Pathology and Cytology, Karolinska University Hospital/Karolinska Institutet, Stockholm, 17176, Sweden

    Joseph W. Carlson MD, PhD

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  1. Eugenia C. Colón MD, PhD
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  2. Joseph W. Carlson MD, PhD
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Correspondence to Joseph W. Carlson MD, PhD .

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Editors and Affiliations

  1. Department of Histopathology, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom

    Nafisa Wilkinson

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© 2014 Springer-Verlag London

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Colón, E.C., Carlson, J.W. (2014). Serous Neoplasms of the Ovary. In: Wilkinson, N. (eds) Pathology of the Ovary, Fallopian Tube and Peritoneum. Essentials of Diagnostic Gynecological Pathology. Springer, London. https://doi.org/10.1007/978-1-4471-2942-4_9

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  • DOI: https://doi.org/10.1007/978-1-4471-2942-4_9

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  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-2941-7

  • Online ISBN: 978-1-4471-2942-4

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