Benefits and Risks of Different Regimen of Intermittent Hypoxic Training

  • Katerina RozovaEmail author
  • Olga Gonchar
  • Iryna N. Mankovska


Intermittent hypoxia could effectively stimulate various metabolic processes, and this ­phenomenon is increasingly used in sport and medicine practice. However, the mode of intermittent hypoxia training (IHT) is important for achieving adequate protective effects. It is known that the short and chronic intermittent hypoxia may have serious pathophysiological consequences in organism’s tissues, depending on severity and duration of the hypoxia insult. This chapter investigates the effects of various modes of IHT differing by the intensity and duration of hypoxic exposure on morphology and antioxidant status of the heart and lung tissues. The results showed that the IHT mode with more severe but shorter hypoxic component led to the prooxidant/antioxidant imbalance in the myocardial and lung tissues, which was accompanied with significant disorders in their morphology and ­function. Moderate hypoxic exposure of different durations promoted the maintenance of optimal antioxidant homeostasis and development of compensatory adaptive changes in tissue structure.


Intermittent Hypoxia Hypoxic Exposure Chronic Intermittent Hypoxia Hypoxia Insult Hypoxic Training 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



Intermittent hypoxic training


Lipid peroxidation


Respiratory tract lining fluid


Thiobarbituric acid-reactive substances


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Copyright information

© Springer-Verlag London 2012

Authors and Affiliations

  • Katerina Rozova
    • 1
    Email author
  • Olga Gonchar
    • 1
  • Iryna N. Mankovska
    • 1
  1. 1.Department of HypoxiaBogomoletz Institute of Physiology, National Academy of Sciences of UkraineKievUkraine

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