Pancreatic Cancer

  • Yingtai Chen
  • Chengfeng Wang
  • Yawei Zhang


Pancreatic cancer is a fatal malignancy associated with rapid progression. One year relative survival rates are less than 30 %, and nearly all patients die from the disease within 7 years of surgery. It is estimated that 43,920 men and women will be diagnosed with pancreatic cancer and 37,390 will die of the disease in 2012. Although there have been improvements made in the diagnostic and prognosis of pancreatic cancer, these changes are minor. Smoking is the only established nonheritable risk factor for pancreatic cancer; however, only about 30 % of the cases can be attributed to smoking. Although results are inconclusive, obesity, diabetes, alcohol consumption, and chronic pancreatitis have also been suggested as risk factors for pancreatic cancer. Given this poorly understood etiology, prevention of this deadly disease continues to remain a challenge.


Pancreatic cancer Occupational risk factors Chemical production Metal manufacturing Solvents Molecular markers 


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Copyright information

© Springer-Verlag London 2014

Authors and Affiliations

  1. 1.Department of Abdominal Tumours SurgeryCenter of Pancreatic Tumours, Cancer Institute and Hospital, Chinese Academy of Medical SciencesBeijingChina
  2. 2.Department of Environmental Health SciencesYale University, School of Public HealthNew HavenUSA

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