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Transcatheter Aortic Valve Replacement: What the Near-Term Future Holds and What Evidence Is Needed?

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Multimodality Imaging for Transcatheter Aortic Valve Replacement

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Abstract

Transcatheter aortic valve replacement (TAVR) is a rapidly evolving therapy that already has a strong evidence base in both inoperable and high-risk patients with severe calcific aortic stenosis. Its ongoing growth as a treatment modality in the near future demands a rigorous approach to clinical research to provide evidence to support its long-term safety and efficacy. This evidence will come in several important areas: (1) refining the indications for TAVR, (2) improving its safety, and (3) building on the success of the first-generation devices with novel designs and concepts. The indications for this technology are being refined, and although the primary focus is on aortic stenosis, exciting new applications are emerging that will require rigorous evaluation and present new challenges. Improving the safety and efficacy of TAVR is of paramount importance, and there is a growing evidence base that concurrent advances in imaging techniques are helping to reduce complications that can arise with TAVR. Several new TAVR devices are emerging, which are each being evaluated in clinical studies.

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Author information

Authors and Affiliations

  1. Department of Cardiology, Cedars-Sinai Heart Institute, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, CA, 90048, USA

    Hasan Jilaihawi MD, MRCP, Tarun Chakravarty MD & Raj Makkar MD, FACC

Authors
  1. Hasan Jilaihawi MD, MRCP
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  2. Tarun Chakravarty MD
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  3. Raj Makkar MD, FACC
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Correspondence to Hasan Jilaihawi MD, MRCP .

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Editors and Affiliations

  1. NewYork-Presbyterian Hospital, Weill Cornell Medical College, New York, New York, USA

    James K. Min

  2. Departments of Imaging and Medicine, David Geffen UCLA School of Medicine, Cedars-Sinai Medical Center Cedars-Sinai Heart Institute, Los Angeles, California, USA

    Daniel S. Berman

  3. Department of Cardiology, St. Paul’s Hospital, University of British Columbia Department of Radiology, Vancouver, British Columbia, Canada

    Jonathon Leipsic

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Jilaihawi, H., Chakravarty, T., Makkar, R. (2014). Transcatheter Aortic Valve Replacement: What the Near-Term Future Holds and What Evidence Is Needed?. In: Min, J., Berman, D., Leipsic, J. (eds) Multimodality Imaging for Transcatheter Aortic Valve Replacement. Springer, London. https://doi.org/10.1007/978-1-4471-2798-7_7

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