The Negative Effect of a High-Protein–Low-Calcium Diet
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The interdependent influence of the protein and the calcium intake on bone health has been conclusively studied. For obtaining a positive bone effect from nutritional protein, an adequate calcium intake is required, and vice versa. A high-protein intake was first considered as potentially negative for bone, but this fear was not defendable anymore when it became evident that a high-protein intake increases urinary calcium excretion because it stimulates calcium absorption. Protein deficiency was shown to be detrimental to bone, not a high-protein intake. However, some large follow-up studies demonstrated that the combination of a high-protein intake with a low-calcium diet increases fracture risk. This particular nutritional profile seems to be rare, but some cross-sectional studies seem to confirm that.
KeywordsProtein intake Protein/calcium ratio Fracture risk
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