Inflammatory Disorders

  • Fiona Campbell
  • Caroline S. Verbeke


Inflammatory processes affecting the pancreas present clinically as two distinct entities: acute and chronic pancreatitis. Although both exhibit characteristic morphological features, there is a certain overlap, in particular in the pathology of a common complication of both diseases, the pancreatic pseudocyst. In recent years, new types of chronic pancreatitis have been characterized, and attempts are made at using a more etiology-based terminology, such as hereditary chronic pancreatitis, obstructive chronic pancreatitis, and autoimmune pancreatitis. Diagnostic algorithms, consensus guidelines, and practical guidance on the assessment of IgG4 immunohistochemistry are included in the discussion of autoimmune pancreatitis and its differential diagnoses. In addition to the prototypical acute and chronic pancreatitis, other inflammatory processes which may affect the pancreas, either primarily or, more often, as part of a multiorgan or systemic disease (e.g., collagen vascular disease or sarcoidosis), are also included in this chapter.


Acute Pancreatitis Chronic Pancreatitis Pancreatic Duct Severe Acute Pancreatitis Autoimmune Pancreatitis 
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Further Reading

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Copyright information

© Springer-Verlag London 2013

Authors and Affiliations

  • Fiona Campbell
    • 1
  • Caroline S. Verbeke
    • 2
  1. 1.Department of PathologyRoyal Liverpool University HospitalLiverpoolUK
  2. 2.Karolinska Institute, Division of PathologyKarolinska University HospitalStockholmSweden

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