Abstract
Solid-pseudopapillary neoplasm (SPN) is a low-grade malignant epithelial neoplasm of uncertain cellular origin. The morphological appearances and immunohistochemical profile are discussed in this chapter, together with the rare variants. There is also detailed discussion of the differential diagnosis and the morphological features and immunohistochemical profiles (tabulated in Chap. 20) which can be used to distinguish these different diagnostic entities.
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References
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Further Reading
Hruban RH, Pitman MB, Klimstra DS. Tumors of the pancreas, Atlas of tumor pathology, 4th series, fascicle 6. Washington, DC: Armed Forces Institute of Pathology; 2007. p. 231–50, chapter 11.
Klöppel G, Hruban RH, Klimstra DS, Maitra A, Morohoshi T, Notohara K, et al. Solid-pseudopapillary neoplasm of the pancreas. In: Bosman FT, Carneiro F, Hruban RH, Theise ND, editors. WHO classification of tumours of the digestive system, World Health Organization classification of tumours. Lyon: IARC; 2010. p. 327–30, chapter 12.
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Campbell, F., Verbeke, C.S. (2013). Solid-Pseudopapillary Neoplasia. In: Pathology of the Pancreas. Springer, London. https://doi.org/10.1007/978-1-4471-2449-8_18
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DOI: https://doi.org/10.1007/978-1-4471-2449-8_18
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