• Henryk A. Domanski
  • Xiaohua Qian
  • Donald E. Stanley


Methods for percutaneous sampling such as core needle biopsy (CNB) and drill biopsy have, in recent years, emerged as important diagnostic substitutes for open biopsy of bone neoplasms. In addition, fine-needle aspiration cytology (FNAC) has been used for many years in the diagnosis of bone lesions. As early as 1931, Coley and Ellis applied this sampling method to bone neoplasms. To date, several large series of FNA examination of bone lesions have been published. There are several advantages to skeletal FNAC. The procedure is less traumatic than either CNB or open biopsy and can be used safely in difficult sites such as vertebrae or pelvic bone. FNAC allows rapid triage with coordination of further investigations and planning of anticipated therapy.


Giant Cell Tumor Anaplastic Large Cell Lymphoma Ewing Sarcoma Osteoid Osteoma Aneurysmal Bone Cyst 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag London 2014

Authors and Affiliations

  • Henryk A. Domanski
    • 1
  • Xiaohua Qian
    • 2
  • Donald E. Stanley
    • 3
  1. 1.Department of PathologySkåne University HospitalLundSweden
  2. 2.Department of PathologyBrigham & Women’s Hospital, Harvard Medical SchoolBostonUSA
  3. 3.Department of PathologyMaine Medical CenterPortlandUSA

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